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Income Taxes - Narrative (Details) - USD ($)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Jan. 01, 2022
Operating Loss Carryforwards [Line Items]        
Statutory tax rate 21.00% 21.00% 21.00%  
Valuation allowance $ 243,811,000 $ 130,569,000    
Valuation allowance, increase (decrease), amount 113,200,000      
Deferred tax assets, deferred expense, capitalized research and development costs increase (decrease)       $ 43,200,000
Interest and penalties accrued 0 $ 0    
Unrecognized tax benefits that would impact effective tax rate, if recognized 0      
United States        
Operating Loss Carryforwards [Line Items]        
Net operating loss carryforwards 597,000,000      
Net operating loss carryforwards, not subject to expiration 553,800,000      
Net operating loss carryforwards, subject to expiration $ 43,200,000      
Research and development activities, amortized over period 5 years      
Capitalized expenses, amortization period       5 years
United States | Research Tax Credit Carryforward        
Operating Loss Carryforwards [Line Items]        
Research and development tax credit carryforwards $ 21,100,000      
U.S. State        
Operating Loss Carryforwards [Line Items]        
Net operating loss carryforwards 547,800,000      
U.S. State | Research Tax Credit Carryforward        
Operating Loss Carryforwards [Line Items]        
Research and development tax credit carryforwards 3,900,000      
Tax credit carryforward, subject to expiration 50,000.00      
Tax credit carryforward, not subject to expiration $ 4,300,000      
Foreign Tax Authority        
Operating Loss Carryforwards [Line Items]        
Research and development activities, amortized over period 15 years      
Capitalized expenses, amortization period       15 years