Exhibit 99.1

CENTOGENE Reports First-Quarter 2020 Financial Results and Corporate Progress

Cambridge, MA, USA & Rostock/Berlin, Germany, June 15, 2020 (GLOBE NEWSWIRE) — Centogene N.V. (Nasdaq: CNTG), a commercial-stage company focused on rare diseases that transforms real-world clinical and genetic data into actionable information for patients, physicians, and pharmaceutical companies, today provided an update on its corporate progress and reported its financial results for the three months ended March 31, 2020.

· €12.1 million in revenues, an increase of 13% compared to three months ended March 31, 2019

· Continued expansion of global proprietary rare disease platform with approximately 3.0 billion weighted data points from over 530,000 patients representing 120 different countries as of March 31, 2020

· Over 60 biomarker programs, with over 25 biomarker programs (covering more than 22 diseases) having completed the first validation with mass spectrometry as of March 31, 2020

· Expansion of our COVID-19 testing, and commencement of production and distribution of a sample collection kit, CentoSwab™, to support global efforts to address the pandemic

Prof. Arndt Rolfs, CEO of CENTOGENE, said, “During the first quarter of 2020, we continued our focus on our core business of providing precise medical diagnosis of and accelerating drug development for rare hereditary diseases, while taking important steps to operate our business effectively during COVID-19 and support broader efforts to address this pandemic. We are pleased to report a growth of revenues by 13% for the first quarter 2020, driven by the continuous improvement in businesses of both our Pharma and Diagnostics segments.”

Prof. Arndt Rolfs continued, “As we continue to operate in a COVID-19 environment, it is our pleasure to report that while our quick, initial actions enabled 75% of employees to work from home, we have recently been able to bring back nearly all of our staff into the office by implementing regular testing. Additionally, we have further leveraged our diagnostic expertise to develop and offer a SARS-CoV-2 testing solution for patients around the world — beginning with the sampling system ‘CentoSwab™’ and ending with the CENTOGENE-developed app for patient registration and medical reporting. We expect this diagnostic solution will help global communities begin to return to a new normal and prevent a further outbreak. With COVID-19 pandemic continued spreading across the globe, we have started to see its negative impact to our incumbent business, but expect our commercial COVID-19 testing will help offsetting such negative impact.”

Nimble Response to COVID-19 and Continued Rare Disease Diagnostic Operations

Spearheading Sustainable COVID-19 Testing Capabilities

In March 2020, CENTOGENE announced the commencement of its COVID-19 testing. Starting with employees and essential workers in Rostock, Germany, the Company further expanded the test offering to the nursing homes as well as to the high school students throughout Germany. Since May 2020, the Company is offering its tests to the rest of the world. In addition, CENTOGENE secured necessary reagents and supplies, such as CentoSwab™, to support the logistics and fast diagnosis of COVID-19 since April 2020.

Acquisition of Hamburg Laboratory to Expand Testing Capacities

In April 2020, CENTOGENE announced the opening of a new laboratory in Hamburg, Germany to increase its testing capacity for the COVID-19 virus. The Rostock laboratory will continue to focus on the Company’s core business in rare hereditary diseases and its research efforts in biomarker development.

Three Months Ended March 31, 2020 Financial Highlights

Cash and Cash Equivalents

Cash and cash equivalents as of March 31, 2020 were €33.4 million, compared to €41.1 million as of December 31, 2019.

Revenue

Our revenue is principally derived from the provision of pharmaceutical solutions and diagnostic tests enabled by our knowledge and interpretation-based platform.

Revenue for the three months ended March 31, 2020 was €12.1 million, an increase of approximately €1.4 million, or 13% as compared to the three months ended March 31, 2019. Revenue from our pharmaceutical segment was €4.6 million for the three months ended March 31, 2020, an increase of approximately €0.4 million, or 10.2% as compared to that of the prior period, while the revenue from our diagnostics segment was €7.5 million for the three months ended March 31, 2020, an increase of approximately €1 million, or 14.7% as compared to that of the prior period.

Pharmaceutical segment

Our pharmaceutical segment provides a variety of services to our pharmaceutical partners, including target discovery, early patient recruitment and identification, epidemiological and patient population sizing insights, biomarker discovery and patient monitoring and follow-up. Our information platforms, our access to rare diseases patients and their biomaterials and our ability to develop proprietary technologies including biomarkers enable us to provide services to our pharmaceutical partners in all phases of the drug development process as well as post-commercialization.

We have been successful in entering into collaborations with pharmaceutical partners in the early stages of drug development, which puts us in a position to provide more support to the development process and increases our potential to secure further collaborations for the same drugs.

Revenues in our pharmaceutical segment are generated primarily from collaboration agreements with our pharmaceutical partners, which are structured on a fee per sample basis, milestone basis, fixed fee basis, royalty basis or a combination of these.

The graphs below show our revenues for the three months ended March 31, 2020 and 2019 resulting from our collaborations with our pharmaceutical partners split between drug development stage, as well as split between different fee structure:

We anticipate the proportion of WES and WGS as a percentage of total test requests in the future will continue to increase. The data collected from our diagnostics services, together with the biomaterials, allow us to continue to grow our global biorepository and our rare disease platform repository.

Research and development expenses (“R&D”)

Our R&D expenses for the three months ended March 31, 2020 were €2.7 million, an increase of approximately €1 million, or 58.2% as compared to the prior period. The increase is primarily attributable to expenses associated with the expansion of our proprietary information platform, as well as development of new products and solutions.

General administrative expenses (“G&A”)

Our G&A expenses for the three months ended March 31, 2020 were €7.9 million, an increase of approximately €2 million, or 33.6% as compared to the prior period. The increase is primarily due to an increase in personnel costs and operating expenses as a result of the expansion of the business. The increase was also due to costs associated with operating as a public company, such as additional legal, accounting, corporate governance and investor relations expenses, and higher directors’ and officers’ insurance premiums. The general administrative expenses also included share-based compensation expenses of €1.1 million for the three months ended March 31, 2020, as compared to €2.1 million for the three months ended March 31, 2019.

Other operating expenses

Considering the impact of the COVID-19 pandemic to the global economy and the unforeseeable potential magnitude of the ultimate disruptions to different businesses, we have taken this into consideration when assessing the credit risk, in particular regarding the MENA region for the diagnostic segment as it represents the majority of that segment’s revenue. Such assessment resulted in an additional credit loss of €1.2 million for the three months ended March 31, 2020. The amount of credit loss made for the three months ended March 31, 2019 amounted to €0.3 million.

Comprehensive loss attributable to equity holders

The comprehensive loss attributable to equity holders for the three months ended March 31, 2020 was €8.6 million or €0.43 per share, as compared to €5.2 million or €0.33 per share for the prior year.

Basic and diluted loss per share is calculated by dividing loss for the year attributable to equity holders of the Group by the weighted average number of shares outstanding of 19,861,340 and 15,861,340 during the three months ended March 31, 2020 and 2019 respectively.

Additional information regarding these financials is included in the notes to the unaudited interim condensed consolidated financial statements as of and for the three months ended March 31, 2020 attached as Exhibit 99.2 to this Form 6-K, which can be found by visiting EDGAR on the U.S. Securities and Exchange Commission website at www.sec.gov.

Centogene N.V.

for the three months ended March 31, 2019 and 2020

Consolidated statements of comprehensive loss

	For the three months ended March 31,
	2019		2020
	(unaudited, € in thousands, except for loss per share)
Consolidated statement of comprehensive loss:
Revenue	10,715		12,105
Cost of sales	6,744		7,018
Gross profit	3,971		5,087
Research and development expenses	1,701		2,691
General administrative expenses	5,910		7,898
Selling expenses	2,011		2,326
Other operating income	1,098		945
Other operating expenses	342		1,275
Operating loss	(4,895	)	(8,158	)
Interest and similar income	8		—
Interest and similar expense	220		449
Finance costs, net	(212	)	(449	)
Loss before taxes	(5,107	)	(8,607	)
Income tax expenses	174		129
Loss for the year	(5,281	)	(8,736	)
Other comprehensive income	2		76
Total comprehensive loss for the period	(5,279	)	(8,660	)
Total comprehensive loss for the period attributable to the equity holders of the parent	(5,210	)	(8,599	)

Loss per share — Basic and diluted (in €)	(0.33	)	(0.43	)

Centogene N.V.

for the three months ended March 31, 2019 and 2020

Supplemental selected segment information

	For the three months ended March 31,
	2019	2020
	(€ in thousands)
Revenue by Segment
Pharmaceutical	4,130	4,550
Diagnostics	6,585	7,555
Total Revenue	10,715	12,105

	For the three months ended March 31,
	2019	2020
	(€ in thousands)
Segment Adjusted EBITDA
Pharmaceutical	2,944	2,608
Diagnostics	11	87
Total segment Adjusted EBITDA	2,955	2,695

Reconciliation of segment Adjusted EBITDA to	For the three months ended March 31,
Group loss for the period	2019		2020
	(€ in thousands)
Reported Segment Adjusted EBITDA	2,955		2,695
Corporate expenses	(3,820	)	(7,712	)
	(865	)	(5,017	)
Share-based payment expenses	(2,633	)	(1,057	)
Depreciation and amortization	(1,397	)	(2,084	)
Operating loss	(4,895	)	(8,158	)
Finance costs, net	(212	)	(449	)
Income tax expenses	(174	)	(129	)
Loss for the period	(5,281	)	(8,736	)

Centogene N.V.

As at December 31, 2019 and March 31, 2020

Consolidated statements of financial position

Assets	Dec 31, 2019	Mar 31, 2020
	(unaudited, € in thousands)
Non-current assets
Intangible assets	14,145	14,518
Property, plant and equipment	8,376	8,709
Right-of-use assets	24,932	24,710
Other assets	1,948	2,098
	49,401	50,035
Current assets
Inventories	1,809	5,849
Trade receivables	16,593	14,646
Other assets	8,612	8,890
Cash and cash equivalents	41,095	33,381
	68,109	62,766
	117,510	112,801

Equity and liabilities	Dec 31, 2019		Mar 31, 2020
Equity
Issued capital	2,383		2,383
Capital reserve	98,099		99,156
Retained earnings and other reserves	(40,622	)	(49,221	)
Non-controlling interests	(938	)	(731	)
	58,922		51,587
Non-current liabilities
Non-current loans	1,578		768
Lease liabilities	18,069		18,826
Deferred tax liabilities	—		121
Government grants	9,941		9,773
	29,588		29,488
Current liabilities
Government grants	1,348		1,364
Current loans	3,688		3,852
Lease liabilities	3,635		3,625
Trade payables	8,554		10,173
Other liabilities	11,775		12,712
	29,000		31,726
	117,510		112,801

Centogene N.V.

for the three months ended March 31, 2019 and 2020

Consolidated statements of cashflow

	For the three months ended March 31
	2019		2020
	(unaudited, € in thousands)
Loss before taxes	(5,107	)	(8,607	)
Amortization and depreciation	1,397		2,084
Interest income	(8	)	—
Interest expense	220		449
Expected credit loss allowances on trade receivables	340		1,174
Share-based payment expenses	2,633		1,057
Other non-cash items	(268	)	(192	)
Changes in operating assets and liabilities:
Inventories	(275	)	(4,040	)
Trade receivables	(2,073	)	773
Other assets	(967	)	(234	)
Trade payables	507		1,619
Other liabilities	328		1,751
Cash flow used in operating activities	(3,273	)	(4,166	)

Cash paid for investments in intangible assets	(1,113	)	(1,191	)
Cash paid for investments in property, plant and equipment	(441	)	(644	)
Grant received for investment in property, plant and equipment	—		207
Interest received	8		—
Cash flow used in investing activities	(1,546	)	(1,628	)

Cash received from loans	1,864		414
Cash repayment of loans	(451	)	(1,060	)
Cash repayments of lease liabilities	(461	)	(1,044	)
Interest paid	(220	)	(230	)
Cash flow generated from/(used) in financing activities	732		(1,920	)

Changes in cash and cash equivalents	(4,087	)	(7,714	)
Cash and cash equivalents at the beginning of the period	9,222		41,095
Cash and cash equivalents at the end of the period	5,135		33,381

Call Instructions

Centogene will host a conference call to discuss its financial results for the three months ended March 31, 2020 on Monday, June 15, 2020 at 8 a.m. Eastern Time. The call on June 15, 2020 can be accessed by dialing U.S. toll free +1 877 870 9135 or U.K. +44 (0) 800 279 6619 up to 10 minutes prior to the start of the call and providing the conference ID number 4799325. A presentation and webcast of the conference call can be accessed on the Investor Relations page of our website at http://investors.centogene.com.

About CENTOGENE

CENTOGENE engages in diagnosis and research around rare diseases transforming real-world clinical and genetic data into actionable information for patients, physicians, and pharmaceutical companies. Our goal is to bring rationality to treatment decisions and to accelerate the development of new orphan drugs by using our extensive rare disease knowledge, including epidemiological and clinical data, as well as innovative biomarkers. CENTOGENE has developed a global proprietary rare disease platform based on our real-world data repository with approximately 3.0 billion weighted data points from over 530,000 patients representing over 120 different countries as of March 31, 2020.

The Company’s platform includes epidemiologic, phenotypic, and genetic data that reflects a global population, and also a biobank of these patients’ blood samples. CENTOGENE believes this represents the only platform that comprehensively analyzes multi-level data to improve the understanding of rare hereditary diseases, which can aid in the identification of patients and improve our pharmaceutical partners’ ability to bring orphan drugs to the market. As of March 31, 2020, the Company collaborated with 39 pharmaceutical partners covering over 45 different rare diseases.

Important Notice and Disclaimer

This press release contains statements that constitute “forward looking statements” as that term is defined in the United States Private Securities Litigation Reform Act of 1995, including statements that express the Company’s opinions, expectations, beliefs, plans, objectives, assumptions or projections regarding future events or future results, in contrast with statements that reflect historical facts. Examples include discussion of our strategies, financing plans, growth opportunities and market growth. In some cases, you can identify such forward-looking statements by terminology such as “anticipate,” “intend,” “believe,” “estimate,” “plan,” “seek,” “project” or “expect,” “may,” “will,” “would,” “could” or “should,” the negative of these terms or similar expressions. Forward looking statements are based on management’s current beliefs and assumptions and on information currently available to the Company. However, these forward-looking statements are not a guarantee of our performance, and you should not place undue reliance on such statements. Forward-looking statements are subject to many risks, uncertainties and other variable circumstances, such as negative worldwide economic conditions and ongoing instability and volatility in the worldwide financial markets, the effects of the COVID-19 pandemic on our business and results of operations, possible changes in current and proposed legislation, regulations and governmental policies, pressures from increasing competition and consolidation in our industry, the expense and uncertainty of regulatory approval, including from the U.S. Food and Drug Administration, our reliance on third parties and collaboration partners, including our ability to manage growth and enter into new client relationships, our dependency on the rare disease industry, our ability to manage international expansion, our reliance on key personnel, our reliance on intellectual property