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Stock-Based Compensation - Additional Information (Details) - USD ($)
1 Months Ended 12 Months Ended
Jan. 01, 2022
Jul. 02, 2020
Jul. 31, 2020
Dec. 31, 2022
Dec. 31, 2021
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]          
Reserved shares of common stock for issuance       14,869,885 13,445,714
Common stock, par value       $ 0.0001 $ 0.0001
Stock-based compensation expense       $ 41,315,000 $ 43,975,000
Restricted Common Stock          
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]          
Number of shares granted       1,632,996  
Unrecognized stock-based compensation cost       $ 27,400,000  
Weighted average period of cost expected to be recognized       2 years 6 months 14 days  
Stock Options          
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]          
Weighted average period of cost expected to be recognized       2 years 2 months 12 days  
Aggregate intrinsic value of options exercised       $ 0 $ 300,000
Weighted average grant-date fair value of stock options granted       $ 5.61 $ 24.76
Weighted average grant-date fair value of stock options vested       $ 19.16 $ 13.61
Unrecognized stock-based compensation expenses       $ 50,500,000  
2018 Equity Incentive Plan          
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]          
Awards vesting period       4 years  
Awards contractual term       10 years  
Common stock shares granted       6,715,415  
Number of shares of common stock issuable upon exercise of outstanding options       64,042  
Reserved shares of common stock for issuance       0  
2018 Equity Incentive Plan | Restricted Common Stock          
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]          
Number of shares granted       6,616,772  
2020 Stock Option and Grant Plan          
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]          
Awards vesting period   4 years      
Awards contractual term   10 years      
Common stock authorized for issuance   8,008,734      
Cumulative increase in number shares reserved for issuance, percentage   5.00%      
Shares added to number of available shares under plan 3,528,817        
Common stock issuable upon exercise of outstanding options       7,858,755  
2020 Stock Option and Grant Plan | Restricted Common Stock          
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]          
Number of shares granted       3,076,516  
2020 Stock Option and Grant Plan | Stock Available For Grant          
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]          
Reserved shares of common stock for issuance       4,253,680 3,812,396
2020 Employee Stock Purchase Plan          
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]          
Reserved shares of common stock for issuance     611,354 454,302  
Percentage of payroll deductions of base salary or wages     15.00%    
Percentage of maximum discount on purchase of shares of common stock     15.00%    
Offering period, description       (i) on the first trading day of the offering period or (ii) the last day of any offering period. The Company utilizes the Black Scholes option pricing model to compute the fair market value of the shares and compensation expense is recognized over the offering period. The first ESPP offering period was shortened in duration to three months and commenced on April 1, 2022 and ended on June 30, 2022. New six-month offering periods will commence each January 1 and July 1 thereafter during the term of the plan, with the administrator having the right to establish different offering periods.  
Cumulative increase in number shares reserved for issuance, percentage     1.00%    
Common stock, par value     $ 0.0001    
Annual increase in number of shares reserved for issuance     1,222,707    
Purchase of common stock under the employee stock purchase plan       157,052  
Share issued, average price per share       $ 3.42  
Cash received from purchases under the ESPP       $ 500,000  
Stock-based compensation expense       $ 200,000  
2020 Employee Stock Purchase Plan | Maximum          
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]          
Base salary or wages     $ 25,000