Stock-Based Compensation (Tables)

12 Months Ended

Dec. 31, 2022

Stock-Based Compensation

Schedule of fair value assumptions

	December 31,		December 31,
	2022		2021
Risk-free interest rate		1.99%		0.95%
Expected term (in years)		6.03		5.97
Expected volatility		79.71%		77.55%
Expected dividend yield		—		—

Schedule of stock option activity

				Weighted
		Weighted		Average
		Average		Remaining
	Number of	Exercise		Contractual	Aggregate
	Shares	Price		Term	Intrinsic Value
				(in years)	(in thousands)
Outstanding as of December 31, 2021	5,768,028	$	15.99	8.82	$	11,365
Granted	3,293,640		5.53	—		—
Exercised(1)	(115,448)		3.06	—		—
Forfeited	(561,362)		23.64	—		—
Outstanding as of December 31, 2022(2)	8,384,858	$	8.59	8.30	$	262
Options vested and exercisable as of December 31, 2022	3,270,694	$	10.21	7.79	$	215
Options expected to vest as of December 31, 2022	5,114,164	$	7.56	8.63	$	47

(1) Exercised amount includes vesting of early exercised options.

(2) Balance as of December 31, 2022 includes 18,640 unvested early exercised stock options.

Summary of restricted stock activity

	Number of Shares	Grant Date Fair Value
Unvested restricted stock as of December 31, 2021	493,185	$	2.40
Granted	—
Vested	(197,274)		2.40
Forfeited	—
Unvested restricted stock as of December 31, 2022	295,911	$	2.40

Schedule of stock-based compensation expense

	Years Ended December 31,
	2022		2021
Research and development	$	12,462	$	9,346
General and administrative		6,367		6,567
Total	$	18,829	$	15,913