Stock-Based Compensation (Tables)

12 Months Ended

Dec. 31, 2022

Share-Based Payment Arrangement [Abstract]

Summary of Option Activity Under 2011 Plan and 2020 Plan

The following is a summary of option activity under the 2011 Plan and the 2020 Plan:

	Number of Shares			Weighted- Average Exercise Price Per Share		Weighted- Average Remaining Contractual Term (In Years)
Outstanding at December 31, 2020		3,596,444		$	2.27		7.73
Granted		215,898			3.88		—
Exercised		(112,268	)		0.70		—
Forfeited		(40,708	)		0.38		—
Cancelled		—			—		—
Outstanding at December 31, 2021		3,659,366			2.43		6.99
Granted		869,887			1.00		—
Exercised		(21,854	)		2.02		—
Forfeited		(113,030	)		1.28		—
Cancelled		—			—		—
Outstanding at December 31, 2022		4,394,369			2.19		6.20
Exercisable at December 31, 2022		3,497,813			2.33		1.64

Schedule of Estimated Assumptions of Weighted-Average Fair Values of Options Granted

The weighted-average fair values of options granted in the years ended December 31, 2022 and 2021 were $0.64 and $2.24, per share, respectively, and were calculated using the following estimated assumptions:

	Year ended December 31,
	2022			2021
Weighted-average risk-free interest rate		2.17	%		0.59	%
Expected dividend yield		0.00	%		0.00	%
Expected volatility		84.88	%		82.22	%
Expected terms	4.39 years			3.97 years

Summary of Stock-Based Compensation Expense for Stock Options Granted to Employees and Non-Employees

The following table summarizes the stock-based compensation expense for stock options granted to employees and non-employees:

	Year ended December 31,
	2022		2021
Research and development	$	120,671	$	665,834
Selling, general and administrative		337,476		866,042
Total stock-based compensation expense	$	458,147	$	1,531,876