Consolidated Statements of Redeemable Convertible Preferred Stock and Stockholders' Equity - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Other Comprehensive Income (Loss)	Accumulated Deficit	Private Placement	Private Placement Common Stock	Private Placement Additional Paid-in Capital	ATM Offering	ATM Offering Common Stock	ATM Offering Additional Paid-in Capital
Beginning Balance at Dec. 31, 2020	$ 245,561	$ 573	$ 642,633	$ (9)	$ (397,636)
Beginning Balance, Shares at Dec. 31, 2020		57,254,178
Issuance of common stock from initial public offering/private placement/At-the-Market offering, net of issuance costs						$ 252,005	$ 28	$ 251,977	$ 496,623	$ 49	$ 496,574
Issuance of common stock from initial public offering/private placement/At-the-Market offering, net of issuance costs, Shares							2,795,700			4,907,195
Issuance of common stock for success payment liability	30,000	$ 4	29,996
Issuance of common stock for success payment liability, Shares		349,650
Issuance of common stock to acquire Guide	120,032	$ 10	120,022
Issuance of common stock to acquire Guide, Shares		1,087,153
Vesting of restricted common stock		$ 10	(10)
Vesting of restricted common stock, Shares		1,020,887
Stock-based compensation	43,570		43,570
Exercise of common stock options	9,626	$ 10	9,616
Exercise of common stock options, Shares		974,662
Other comprehensive income (loss)	(41)			(41)
Net Income (Loss)	(370,638)				(370,638)
Ending Balance at Dec. 31, 2021	826,738	$ 684	1,594,378	(50)	(768,274)
Ending Balance, Shares at Dec. 31, 2021		68,389,425
Purchase of common stock under ESPP	3,075		3,075
Purchase of common stock under ESPP, Shares		70,073
Issuance of common stock from initial public offering/private placement/At-the-Market offering, net of issuance costs									108,076	$ 19	108,057
Issuance of common stock from initial public offering/private placement/At-the-Market offering, net of issuance costs, Shares										1,909,103
Vesting of restricted common stock		$ 4	(4)
Vesting of restricted common stock, Shares		424,303
Stock-based compensation	84,321		84,321
Exercise of common stock options	2,732	$ 5	2,727
Exercise of common stock options, Shares		484,435
Other comprehensive income (loss)	(2,380)			(2,380)
Net Income (Loss)	(289,088)				(289,088)
Ending Balance at Dec. 31, 2022	733,474	$ 712	1,792,554	(2,430)	(1,057,362)
Ending Balance, Shares at Dec. 31, 2022		71,277,339
Purchase of common stock under ESPP	3,032	$ 1	3,031
Purchase of common stock under ESPP, Shares		130,403
Issuance of common stock from initial public offering/private placement/At-the-Market offering, net of issuance costs									$ 235,938	$ 70	$ 235,868
Issuance of common stock from initial public offering/private placement/At-the-Market offering, net of issuance costs, Shares										6,952,703
Issuance of unregistered common shares in connection with license agreement	33,600	$ 20	33,580
Issuance of unregistered common shares in connection with license agreement, shares		2,004,811
Vesting of restricted common stock		$ 5	(5)
Vesting of restricted common stock, Shares		469,531
Stock-based compensation	98,647		98,647
Exercise of common stock options	$ 6,131	$ 8	6,123
Exercise of common stock options, Shares	797,709	797,709
Other comprehensive income (loss)	$ 3,034			3,034
Net Income (Loss)	(132,527)				(132,527)
Ending Balance at Dec. 31, 2023	$ 981,329	$ 816	$ 2,169,798	$ 604	$ (1,189,889)
Ending Balance, Shares at Dec. 31, 2023		81,632,496