Net loss per share

12 Months Ended

Dec. 31, 2021

Net loss per share

Net loss per share

11.         Net loss per share

Basic and diluted net loss per share was calculated as follows:

	Year Ended December 31,
	2021		2020		2019
Numerator:
Net loss	$	(100,777)	$	(79,207)	$	(43,755)
Denominator:
Weighted average common shares outstanding, basic and diluted		34,827,385		31,463,248		15,070,728
Net loss per share, basic and diluted	$	(2.89)	$	(2.52)	$	(2.90)

The Company excluded 8,127 shares, 31,215 shares and 49,568 shares of restricted common stock, presented on a weighted average basis, from the calculations of basic net loss per share for the years ended December 31, 2021, 2020 and 2019, respectively, because those shares had not vested.

	Year Ended December 31,
	2021	2020	2019
Options to purchase common stock	5,221,094	3,733,312	3,096,555
Unvested restricted common stock	—	33,614	155,149
	5,221,094	3,766,926	3,251,704