Sale of Nonfinancial Assets - Additional Information (Details) - USD ($) $ in Thousands		1 Months Ended		3 Months Ended		9 Months Ended
	Mar. 31, 2022	Oct. 31, 2022	Jun. 30, 2022	Sep. 30, 2022	Mar. 31, 2022	Sep. 30, 2023	Sep. 30, 2022	Dec. 31, 2022	[1]	May 31, 2022	Mar. 04, 2022
Asset Acquisition [Line Items]
Gross proceeds from sale of priority review voucher						$ 0	$ 110,000
Loss on sale of certain assets						0	6,261
Intangible assets, net						26,917		$ 28,712
Priority Review Voucher
Asset Acquisition [Line Items]
Definitive agreement to sell										$ 110,000
Gross proceeds from sale of priority review voucher			$ 110,000
Gain recognized, net of transactions costs							$ 107,900
Disposal Group, Not Discontinued Operation, Gain (Loss) on Disposal, Statement of Income or Comprehensive Income [Extensible Enumeration]				Other Nonoperating Income (Expense)			Other Nonoperating Income (Expense)
Origin-Sentynl APA
Asset Acquisition [Line Items]
Upfront payment received	$ 10,000
Intangible assets, net						16,300
Regulatory-based milestone payment		$ 3,500
Origin-Sentynl APA | Other income (expense), net
Asset Acquisition [Line Items]
Loss on sale of certain assets					$ 6,300
Origin-Sentynl APA | Maximum [Member]
Asset Acquisition [Line Items]
Potential sales milestone payments											$ 4,500
Regulatory-based milestone payment						$ 1,000

[1] The condensed consolidated balance sheet as of December 31, 2022 is derived from the audited consolidated financial statements as of that date.