In-licensing Agreements - Additional Information (Details)	1 Months Ended		3 Months Ended		6 Months Ended
	Aug. 31, 2022 License	Mar. 31, 2017 USD ($)	Jun. 30, 2023 USD ($)	Jun. 30, 2022 USD ($)	Jun. 30, 2023 USD ($)	Jun. 30, 2022 USD ($)	Aug. 31, 2016 USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Research and development expense			$ 107,488,000	$ 108,400,000	$ 200,349,000	$ 216,049,000
Eidos Therapeutics, Inc | Stanford License Agreement | Leland Stanford Junior University
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
License fees		$ 10,000
Milestone payments							$ 1,000,000
License agreement of percentage					10.00%
TheRas, Inc | Leidos Biomedical Research License and Cooperative Research and Development Agreements | Leidos Biomedical Research, Inc
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Research and development expense			700,000	1,300,000	$ 1,200,000	1,700,000
Number of license agreements | License	2
QED Therapeutics, Inc | Foundation Medicine Diagnostics Agreement | Foundation Medicine, Inc
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Research and development expense			$ 0	$ 400,000	$ 0	$ 1,000,000