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Equity Method and Other Equity Investments - Additional Information (Detail)
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Oct. 31, 2019
USD ($)
Director
shares
Dec. 31, 2021
USD ($)
Sep. 30, 2021
USD ($)
Sep. 30, 2022
USD ($)
Sep. 30, 2021
USD ($)
Dec. 31, 2021
USD ($)
Nov. 01, 2021
Schedule Of Equity Method Investments [Line Items]              
Fair value of warrants   $ 2,100,000   $ 700,000   $ 2,100,000  
LianBio | Equity Method Investee's IPO              
Schedule Of Equity Method Investments [Line Items]              
Ownership interest             4.70%
Gain on conversion from equity method investment to investment in equity securities   $ 68,500,000          
Unrealized loss on ongoing mark-to-market adjustments of investment in equity security       $ 58,500,000   $ 37,700,000  
Bridge Bio Pharma Limited Liability Company | Entities Affiliated With Perceptive Life Sciences Master Fund Ltd | LianBio              
Schedule Of Equity Method Investments [Line Items]              
Ownership interest 10.00%            
Number of directors appoint or removal | Director 1            
Ownership interest, value $ 3,800,000            
Impairments related investment     $ 0   $ 0    
Warrant to purchase percentage 10.00%            
Warrants to purchase common stock | shares 347,569