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Income Taxes - Reconciliation of Income Tax Expense (Details) - USD ($)
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Income Tax Disclosure [Abstract]      
Tax benefit at federal statutory rate $ (18,573,000) $ (3,384,000) $ (1,367,000)
State taxes (2,748,000) (232,000) (90,000)
Research tax credits (475,000) (427,000) (165,000)
Change in valuation allowance 15,062,000 3,958,000 1,694,000
Change in fair value of convertible notes 5,756,000 0 0
Other 978,000 85,000 (72,000)
Expense/(Benefit) for income taxes $ 0 $ 0 $ 0