Income Taxes - Summary of Tax Effects of Temporary Differences Portions of Company's Deferred Tax Assets and Liabilities (Details) - USD ($) $ in Thousands	Dec. 31, 2020	Dec. 31, 2019
Deferred tax assets:
Net operating losses	$ 77,467	$ 66,170
Tax credits	33,753	26,254
Stock-based compensation	20,971	22,299
Accrued compensation and related expenses	3,012	3,513
Lease liabilities	20,475	22,322
Financing related	11,090	9,033
Intangible assets	75,093	72,226
Other	1,474	2,003
Total deferred tax assets:	243,335	223,820
Valuation allowance	(201,814)	(174,921)
Total deferred tax assets, net of valuation allowance:	41,521	48,899
Deferred tax liabilities:
Depreciation and amortization	(867)	(8,708)
Goodwill	(25,792)	(23,047)
Right-of-use assets	(17,565)	(19,077)
Total deferred tax liabilities:	(44,224)	(50,832)
Total net deferred tax liabilities:	$ (2,703)	$ (1,933)