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Related Party Agreements and Transactions - Narrative (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Related Party Transaction [Line Items]      
Restricted cash $ 0 $ 11 $ 11
Bayer      
Related Party Transaction [Line Items]      
Asset purchase refund $ 16 $ 633  
Lilly | Transitional Services Agreement      
Related Party Transaction [Line Items]      
Mark-up rate 7.00%