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Note 11 - License, Research and Collaboration Agreements (Details Textual) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended
Nov. 30, 2018
Mar. 31, 2023
Jun. 30, 2023
ABL Bio Agreement [Member]      
Upfront Payment $ 5,000    
Development Milestone Payment 6,000    
Maximum Development and Regulatory Milestone Payments 96,000    
ABL Bio Agreement [Member] | Oncology [Member]      
Maximum Commercial Milestone Payments and Royalties 303,000    
ABL Bio Agreement [Member] | Ophthalmology [Member]      
Maximum Development and Regulatory Milestone Payments 75,000    
Maximum Commercial Milestone Payments and Royalties $ 110,000    
Adimab Agreement [Member]      
Milestone Payments Paid   $ 0  
Milestone Payment Obligation     $ 2,000