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Summary of Significant Accounting Policies - Additional Information (Details)
12 Months Ended
Jan. 01, 2021
USD ($)
Dec. 31, 2021
USD ($)
Segment
$ / shares
shares
Dec. 31, 2020
USD ($)
$ / shares
shares
Summary Of Significant Accounting Policies [Line Items]      
Stock conversion ratio description   Upon the closing of the Merger, the common and convertible preferred units of Compass Therapeutics LLC were converted into the Company’s common stock. The Company effected a 0.15-for-one stock conversion ratio for its issued and outstanding convertible preferred units. Common units were converted using the same ratio after factoring in the relevant strike price of each grant.  
Common units outstanding | shares   0  
Convertible preferred units outstanding | shares   0  
Preferred stock, shares authorized | shares   10,000,000 10,000,000
Preferred stock, par value | $ / shares   $ 0.0001 $ 0.0001
Common stock, shares authorized | shares   300,000,000 300,000,000
Common stock, par value | $ / shares   $ 0.0001 $ 0.0001
Number of operating segments | Segment   1  
Restricted cash   $ 0 $ 200,000
Letter of credit     100,000
Impairment losses on long-lived assets   0 0
Expected dividend yield   0  
Income tax expense   0 32,000
Operating lease, right-of-use ("ROU") asset   4,089,000 0
Operating lease liabilities   $ 4,037,000  
ASU 2016-02      
Summary Of Significant Accounting Policies [Line Items]      
Change in accounting principle, accounting standards update, adopted true    
Change in accounting principle, accounting standards update, adoption date Jan. 01, 2021    
Change in accounting principle, accounting standards update, transition option elected [Extensible List] us-gaap:AccountingStandardsUpdate201602RetrospectiveMember    
Operating lease, right-of-use ("ROU") asset $ 5,100,000    
Operating lease liabilities $ 5,100,000    
ASU 2019-12      
Summary Of Significant Accounting Policies [Line Items]      
Change in accounting principle, accounting standards update, immaterial effect   true  
Common Stock      
Summary Of Significant Accounting Policies [Line Items]      
Purchase price per share | $ / shares   $ 5.00  
Money Market Funds      
Summary Of Significant Accounting Policies [Line Items]      
Cash equivalents   $ 130,000,000.0 $ 43,600,000
Convertible Preferred Units      
Summary Of Significant Accounting Policies [Line Items]      
Stock conversion ratio   0.15