Share-Based Compensation (Tables)

9 Months Ended

Sep. 30, 2024

Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]

Schedule of Share Option Activity

					Weighted-
			Weighted-		Average
			Average		Remaining
		Number of	Exercise		Contractual
		Options	Price		Term (years)
Outstanding at December 31, 2023		8,226,707	$	12.96	6.35	years
Granted		365,100	$	6.16
Forfeited		(318,537)	$	15.69
Outstanding at September 30, 2024		8,273,270	$	12.57	5.68	years
Options exercisable at September 30, 2024		6,673,069	$	12.99	5.10	years
Options vested and expected to vest at September 30, 2024		8,273,270	$	12.57	5.68	years
Aggregate intrinsic value of options outstanding as of September 30, 2024	$	526
Aggregate intrinsic value of options exercisable as of September 30, 2024	$	526

Schedule of Inputs Used in Determining Fair Value of Share Options

	2024	2023
Risk-free interest rate	4.04 - 4.17%	3.91 - 4.11%
Expected volatility	67%	72%
Expected dividend yield	0%	0%
Expected term (in years)	3.6 - 6.1	6.1

Schedule of Restricted Share Unit (RSU) Activity

		Weighted-
	Number of	Average
	Restricted	Grant Date
	Share Units	Fair Value
Outstanding at December 31, 2023	2,661,250	$	15.24
Granted	2,638,500	$	5.97
Vested	(1,002,500)	$	18.14
Forfeited	(45,000)	$	4.87
Outstanding at September 30, 2024	4,252,250	$	8.91

Schedule of Share-Based Compensation Expense

	Three-Month Periods Ended September 30,
	2024		2023
Research and development	$	2,742	$	3,250
General and administrative		3,562		3,803
Total share-based compensation	$	6,304	$	7,053

	Nine-Month Periods Ended September 30,
	2024		2023
Research and development	$	8,450	$	9,569
General and administrative		10,624		11,187
Total share-based compensation	$	19,074	$	20,756

Employee Stock Option

Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]

Schedule of Share-Based Compensation Expense

	Three-Month Periods Ended September 30,
	2024		2023
Research and development	$	1,450	$	2,169
General and administrative		971		1,300
Total share-based compensation	$	2,421	$	3,469

	Nine-Month Periods Ended September 30,
	2024		2023
Research and development	$	4,665	$	6,441
General and administrative		3,048		3,839
Total share-based compensation	$	7,713	$	10,280

Restricted Share Units

Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]

Schedule of Share-Based Compensation Expense

	Three-Month Periods Ended September 30,
	2024		2023
Research and development	$	1,292	$	1,081
General and administrative		2,591		2,503
Total share-based compensation	$	3,883	$	3,584

	Nine-Month Periods Ended September 30,
	2024		2023
Research and development	$	3,785	$	3,128
General and administrative		7,576		7,348
Total share-based compensation	$	11,361	$	10,476