Related Party Transactions - Leases (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Related Party Transaction [Line Items]
Operating lease rent expenses	$ 5,000	$ 3,300
Cash paid	4,969	3,791
ARE East River Science Park LLC [Member]
Related Party Transaction [Line Items]
Operating lease, right of use asset write-off	900
Operating lease liability write-off	1,000
Net gain on write-off of operating lease right of use asset and liability	100
Operating lease rent expenses	$ 0	100
ARE East River Science Park LLC [Member] | Vivarium Space Operating Lease
Related Party Transaction [Line Items]
Operating lease, term of contract	12 months
Cash paid	$ 90	20
Amount due	0	0
Lease commitment	90
ARE East River Science Park LLC [Member] | Vivarium Space Operating Lease | Loss from operations
Related Party Transaction [Line Items]
Operating lease rent expenses	90	20
Kadmon Corporation LLC [Member] | Loss from operations
Related Party Transaction [Line Items]
Operating lease rent expenses	$ 500	$ 600