Income Taxes (Tables)

12 Months Ended

Dec. 31, 2021

Income Tax Disclosure [Abstract]

Summary of Net Operating Loss Carryforwards

	Federal		State/City
United Kingdom	$	164,288	$	—
United States	$	73,568	$	73,308
Other	$	35,296	$	—

Schedule of Company's Pre-Tax Earnings

The Company's pre-tax earnings are as follows (in thousands):

	December 31, 2021		December 31, 2020
United Kingdom	$	(17,056)	$	(41,373)
United States		(49,223)		(13,472)
Other		(13,282)		(3,147)
	$	(79,561)	$	(57,992)

Schedule of Reconciliation of Income Tax Benefit with Amounts at the U.K. Statutory Income Tax Rate

The following table summarizes a reconciliation of income tax benefit compared with the amounts at the UK statutory income tax rate (in thousands):

	December 31, 2021			December 31, 2020
Statutory rate	(15,117)	19.00	%	(11,019)	19.00	%
Permanent differences - other	934	(1.17)	%	1,976	(3.41)	%
RTP and other adjustment	(2,735)	3.44	%	(2,136)	3.68	%
State and local rate, net of federal tax	(5,850)	7.35	%	(1,478)	2.55	%
U.K. tax credit	(1,464)	1.84	%	574	(0.99)	%
U.S. tax credit	(1,491)	1.87	%	(1,242)	2.14	%
Foreign tax rate differential	(540)	0.68	%	(254)	0.44	%
UK rate change (19% & 25% at expected DTA turn)	(10,247)	12.88	%	(2,234)	3.85	%
US state rate change	(447)	0.56	%	25	(0.04)	%
Change in valuation allowance	36,957	(46.45)	%	15,788	(27.22)	%
Actual income tax benefit effective tax rate	—	0.00	%	—	0.00	%

Schedule of Expense/(Benefit) for Income Taxes from Continuing Operations

The Expense/(Benefit) for income taxes from continuing operations consists of the following (in thousands):

	December 31, 2021	December 31, 2020
Current Tax Expense/(Benefit)
United Kingdom	—	—
United States	—	—
Other	—	—
Total Current	—	—
Deferred Tax Expense/(Benefit)
United Kingdom	(16,079)	(9,197)
United States	(17,369)	(5,852)
Other	(3,509)	(739)
Total Deferred	(36,957)	(15,788)
Change in Valuation Allowance	36,957	15,788
Total Income Tax Expense/(Benefit)	—	—

Schedule of Deferred Tax Assets and Liabilities

Deferred Tax Assets/(Liabilities) (in thousands):

	December 31, 2021		December 31, 2020
Deferred Tax Assets:
Net operating loss carryforwards	$	74,007	$	43,831
Share-based compensation		10,314		5,392
R&D credit		7,498		5,819
Lease liability		7,040		6,150
Other		1,481		298
Deferred tax assets		100,340		61,490
Deferred Tax Liabilities:
Indefinite-lived intangibles		(196)		(173)
Depreciation		(3,339)		(2,252)
Right of use assets		(6,733)		(5,929)
Less: valuation allowance		(90,268)		(53,311)
Net deferred tax liability	$	(196)	$	(175)

Schedule of Unrecognized Tax Benefits

	December 31, 2021		December 31, 2020
Unrecognized tax benefits as of January 1	$	513	$	—
Gross increases/(decreases) related to current year		165		138
Gross increases/(decreases) related to prior years		(12)		375
Foreign currency translation		—		—
Unrecognized tax positions as of December 31	$	666	$	513