Significant Agreements and Contracts - Summary of Revenues Disaggregated by Timing of Revenue Recognition (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2024	Sep. 30, 2023	Sep. 30, 2024	Sep. 30, 2023
Effect of exchange rate changes on revenue
Total revenue from Chiesi Collaboration Agreement	$ 9,480	$ 0	$ 105,322	$ 0
Chiesi
Effect of exchange rate changes on revenue
Total revenue from Chiesi Collaboration Agreement	9,480		105,322
Revenue from sale of US license | Point in Time: | Chiesi
Effect of exchange rate changes on revenue
Total revenue from Chiesi Collaboration Agreement	0		76,686
Revenue from sale of ROW license | Point in Time: | Chiesi
Effect of exchange rate changes on revenue
Total revenue from Chiesi Collaboration Agreement	0		12,050
Revenue from PAH research and development service performance obligation satisfied during reporting period | Over Time: | Chiesi
Effect of exchange rate changes on revenue
Total revenue from Chiesi Collaboration Agreement	4,735		8,133
Revenue from PH-ILD research and development service performance obligation satisfied during reporting period | Over Time: | Chiesi
Effect of exchange rate changes on revenue
Total revenue from Chiesi Collaboration Agreement	157		217
Revenue from PAH research and development costs subject to reimbursement | Over Time: | Chiesi
Effect of exchange rate changes on revenue
Total revenue from Chiesi Collaboration Agreement	3,516		6,812
Revenue from PH-ILD research and development costs subject to reimbursement | Over Time: | Chiesi
Effect of exchange rate changes on revenue
Total revenue from Chiesi Collaboration Agreement	1,086		1,419
Effect of exchange rate changes on revenue | Over Time: | Chiesi
Effect of exchange rate changes on revenue
Total revenue from Chiesi Collaboration Agreement	$ (14)		$ 5