Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Jun. 30, 2023	Dec. 31, 2022
Current assets
Cash and cash equivalents	$ 37,004	$ 111,973
Marketable securities	125,122	143,705
Prepaid expenses and other current assets	11,250	6,202
Total current assets	173,376	261,880
Property and equipment, net	3,054	3,981
Operating lease right-of-use assets	4,546	5,909
Other assets	770	680
Total assets	181,746	272,450
Current liabilities
Accounts payable	2,205	1,459
Accrued research and development expenses	12,062	15,626
Current portion of long-term debt	11,613	11,613
Accrued expenses and other current liabilities	14,260	20,532
Total current liabilities	40,140	49,230
Long-term convertible senior notes	196,144	195,709
Debt, non-current portion	6,436	11,988
Operating lease liabilities - long-term	1,826	3,446
Total liabilities	244,546	260,373
Commitments and contingencies (Note 9)
Stockholders' equity (deficit)
Common stock, $0.0001 par value; 700,000,000 shares authorized as of June 30, 2023 and December 31, 2022; 95,452,703 shares issued and outstanding as of June 30, 2023, and 94,478,405 shares issued and 94,423,181 shares outstanding as of December 31, 2022	10	10
Additional paid-in capital	1,061,555	1,044,864
Accumulated deficit	(1,123,884)	(1,032,223)
Accumulated other comprehensive loss	(481)	(574)
Total stockholders' equity (deficit)	(62,800)	12,077
Total liabilities and stockholders' equity (deficit)	$ 181,746	$ 272,450