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Condensed Consolidated Statements of Stockholders' Equity (Deficit) - USD ($)
$ in Thousands
Total
Cumulative Effect, Period of Adoption, Adjustment
Common stock
Additional paid-in capital
Additional paid-in capital
Cumulative Effect, Period of Adoption, Adjustment
Accumulated deficit
Accumulated deficit
Cumulative Effect, Period of Adoption, Adjustment
Accumulated other comprehensive income (loss)
Beginning balance (in shares) at Dec. 31, 2020     73,874,904          
Beginning balance at Dec. 31, 2020 $ 320,684   $ 8 $ 897,607   $ (577,530)   $ 599
Increase (Decrease) in Stockholders' Equity [Roll Forward]                
Vesting of restricted stock (in shares)     238,962          
Exercise of stock option (in shares)     5,721          
Exercise of stock options (in dollars) 15     15        
Stock-based compensation 8,708     8,708        
Issuance of common stock pursuant to Employee Stock Purchase Plan (in shares)     95,004          
Issuance of common stock pursuant to Employee Stock Purchase Plan 759     759        
Issuance of common stock for restricted stock units vested (in shares)     278,559          
Net loss (57,641)         (57,641)    
Other comprehensive loss (441)             (441)
Ending balance (in shares) at Mar. 31, 2021     74,493,150          
Ending balance at Mar. 31, 2021 272,084   $ 8 907,089   (635,171)   158
Beginning balance (in shares) at Dec. 31, 2020     73,874,904          
Beginning balance at Dec. 31, 2020 320,684   $ 8 897,607   (577,530)   599
Increase (Decrease) in Stockholders' Equity [Roll Forward]                
Net loss (177,720)              
Other comprehensive loss (462)              
Ending balance (in shares) at Sep. 30, 2021     75,300,074          
Ending balance at Sep. 30, 2021 169,809   $ 8 924,914   (755,250)   137
Beginning balance (in shares) at Dec. 31, 2020     73,874,904          
Beginning balance at Dec. 31, 2020 $ 320,684   $ 8 897,607   (577,530)   599
Increase (Decrease) in Stockholders' Equity [Roll Forward]                
Accounting Standards Update [Extensible Enumeration] Accounting Standards Update 2020-06 [Member]              
Ending balance (in shares) at Dec. 31, 2021     75,752,664          
Ending balance at Dec. 31, 2021 $ 121,463 $ (44,838) $ 8 932,944 $ (53,527) (811,534) $ 8,689 45
Beginning balance (in shares) at Mar. 31, 2021     74,493,150          
Beginning balance at Mar. 31, 2021 272,084   $ 8 907,089   (635,171)   158
Increase (Decrease) in Stockholders' Equity [Roll Forward]                
Vesting of restricted stock (in shares)     231,710          
Exercise of stock option (in shares)     103,922          
Exercise of stock options (in dollars) 271     271        
Stock-based compensation 8,054     8,054        
Issuance of common stock pursuant to Employee Stock Purchase Plan (in shares)     6,170          
Net loss (59,832)         (59,832)    
Other comprehensive loss 116             116
Ending balance (in shares) at Jun. 30, 2021     74,834,952          
Ending balance at Jun. 30, 2021 220,693   $ 8 915,414   (695,003)   274
Increase (Decrease) in Stockholders' Equity [Roll Forward]                
Vesting of restricted stock (in shares)     228,084          
Exercise of stock option (in shares)     171,252          
Exercise of stock options (in dollars) 1,357     1,357        
Stock-based compensation 7,587     7,587        
Issuance of common stock pursuant to Employee Stock Purchase Plan (in shares)     65,786          
Issuance of common stock pursuant to Employee Stock Purchase Plan 556     556        
Net loss (60,247)         (60,247)    
Other comprehensive loss (137)             (137)
Ending balance (in shares) at Sep. 30, 2021     75,300,074          
Ending balance at Sep. 30, 2021 169,809   $ 8 924,914   (755,250)   137
Beginning balance (in shares) at Dec. 31, 2021     75,752,664          
Beginning balance at Dec. 31, 2021 121,463 (44,838) $ 8 932,944 (53,527) (811,534) 8,689 45
Increase (Decrease) in Stockholders' Equity [Roll Forward]                
Vesting of restricted stock (in shares)     165,675          
Exercise of stock option (in shares)     39,525          
Exercise of stock options (in dollars) 126     126        
Stock-based compensation 10,983     10,983        
Issuance of common stock pursuant to Employee Stock Purchase Plan (in shares)     77,496          
Issuance of common stock pursuant to Employee Stock Purchase Plan 595     595        
Issuance of common stock for restricted stock units vested (in shares)     518,577          
Net loss (57,785)         (57,785)    
Other comprehensive loss (385)             (385)
Ending balance (in shares) at Mar. 31, 2022     76,553,937          
Ending balance at Mar. 31, 2022 30,159   $ 8 891,121   (860,630)   (340)
Beginning balance (in shares) at Dec. 31, 2021     75,752,664          
Beginning balance at Dec. 31, 2021 $ 121,463 $ (44,838) $ 8 932,944 $ (53,527) (811,534) $ 8,689 45
Increase (Decrease) in Stockholders' Equity [Roll Forward]                
Exercise of stock option (in shares) 269,103              
Net loss $ (173,614)              
Other comprehensive loss (630)              
Ending balance (in shares) at Sep. 30, 2022     93,914,200          
Ending balance at Sep. 30, 2022 56,351   $ 10 1,033,385   (976,459)   (585)
Beginning balance (in shares) at Mar. 31, 2022     76,553,937          
Beginning balance at Mar. 31, 2022 30,159   $ 8 891,121   (860,630)   (340)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                
Vesting of restricted stock (in shares)     165,675          
Exercise of stock option (in shares)     8,005          
Exercise of stock options (in dollars) 21     21        
Stock-based compensation 9,999     9,999        
Issuance of common stock pursuant to Employee Stock Purchase Plan (in shares)     8,607          
Net loss (56,466)         (56,466)    
Other comprehensive loss (174)             (174)
Ending balance (in shares) at Jun. 30, 2022     76,736,224          
Ending balance at Jun. 30, 2022 (16,461)   $ 8 901,141   (917,096)   (514)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                
Issuance of common stock in connection with a private offering, net of offering costs (in shares)     16,649,365          
Issuance of common stock in connection with a private offering, net of offering costs of $184 $ 119,928   $ 2 119,926        
Vesting of restricted stock (in shares) 0   165,676          
Exercise of stock option (in shares)     219,573          
Exercise of stock options (in dollars) $ 1,576     1,576        
Stock-based compensation 10,122     10,122        
Issuance of common stock pursuant to Employee Stock Purchase Plan (in shares)     80,362          
Issuance of common stock pursuant to Employee Stock Purchase Plan 620     620        
Issuance of common stock for restricted stock units vested (in shares)     63,000          
Net loss (59,363)         (59,363)    
Other comprehensive loss (71)             (71)
Ending balance (in shares) at Sep. 30, 2022     93,914,200          
Ending balance at Sep. 30, 2022 $ 56,351   $ 10 $ 1,033,385   $ (976,459)   $ (585)