Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Jun. 30, 2022	Dec. 31, 2021
Current assets
Cash and cash equivalents	$ 94,316	$ 183,403
Marketable securities	127,845	141,815
Restricted cash	0	64
Prepaid expenses and other current assets	10,521	6,498
Total current assets	232,682	331,780
Property and equipment, net	4,686	5,320
Operating lease right-of-use assets	7,222	5,477
Other assets	1,254	1,080
Total assets	245,844	343,657
Current liabilities
Accounts payable	3,908	3,244
Accrued research and development expenses	14,270	16,205
Accrued expenses and other current liabilities	26,230	20,410
Total current liabilities	44,408	39,859
Long-term convertible senior notes	195,286	150,038
Debt, non-current portion	17,645	29,079
Operating lease liabilities - long-term	4,966	3,218
Total liabilities	262,305	222,194
Commitments and contingencies (Note 9)
Stockholders' equity
Common stock, $0.0001 par value; 700,000,000 shares authorized as of June 30, 2022 and December 31, 2021; 77,122,798 shares issued and 76,736,225 shares outstanding as of June 30, 2022, and 76,470,588 shares issued and 75,752,664 shares outstanding as of December 31, 2021	8	8
Additional paid-in capital	901,141	932,944
Accumulated deficit	(917,096)	(811,534)
Accumulated other comprehensive (loss) income	(514)	45
Total stockholders' equity (deficit)	(16,461)	121,463
Total liabilities and stockholders' equity	$ 245,844	$ 343,657