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Equity Incentive Plans - Summary of Stock Option Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2022
Dec. 31, 2021
Shares Subject to Options Outstanding, Shares    
Outstanding as of beginning balance (in shares) 9,434,660  
Options granted (in shares) 4,041,165  
Option exercised (in shares) (39,525)  
Options forfeited/cancelled (in shares) (114,608)  
Outstanding as ending balance (in shares) 13,321,692 9,434,660
Options vested and exercisable as of ending balance (in shares) 13,321,692  
Options exercisable as of ending balance (in shares) 5,549,308  
Shares Subject to Options Outstanding, Weighted Average Exercise Price    
Outstanding as of beginning balance (in USD per share) $ 12.24  
Options granted (in USD per share) 11.86  
Option exercised (in USD per share) 3.18  
Options forfeited/cancelled (in USD per share) 15.49  
Outstanding as of ending balance (in USD per share) 12.13 $ 12.24
Options vested and exercisable as of ending balance (in USD per share) 12.13  
Options exercisable as of ending balance (in USD per share) $ 12.40  
Weighted-Average Remaining Contractual Life (in years) 7 years 10 months 24 days 7 years 4 months 24 days
Weighted-Average Remaining Contractual Life (in years), Options vested and exercisable as of end of period 7 years 10 months 24 days  
Weighted-Average Remaining Contractual Life (in years), Options exercisable as of end of period 6 years 6 months  
Aggregate Intrinsic Value $ 7,047,000 $ 15,822,000
Aggregate Intrinsic Value, Options vested and exercisable as of end of period 7,047,000  
Aggregate Intrinsic Value, Options exercisable as of end of period $ 6,670,000