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Income Taxes - Reconciliation of Federal Statutory Income Tax Rate to Effective Income Tax Rate (Detail)
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Income Tax Disclosure [Abstract]      
Federal statutory income tax rate 21.00% 21.00% 34.00%
State income taxes, net of federal benefit     5.73%
Change in valuation allowance (22.12%) (13.17%) (27.97%)
Change in tax law     (11.85%)
Research and experimentation credits 3.81% 0.77%  
Foreign rate differential (1.84%) (1.74%)  
Stock-based compensation   (2.60%)  
In process research and development   (3.92%)  
Other (0.85%) (0.34%) 0.09%