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Equity Incentive Plans - Summary of Stock Option Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2019
Dec. 31, 2018
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]    
Shares Subject to Options Outstanding, as of December 31, 2018 5,107,329  
Shares Subject to Options Outstanding, Options granted 2,390,144  
Shares Subject to Options Outstanding, Option exercised (27,500)  
Shares Subject to Options Outstanding, Outstanding as of March 31, 2019 7,469,973 5,107,329
Shares Subject to Options Outstanding, Options vested and exercisable as of March 31, 2019 160,682  
Weighted-Average Exercise Price, Outstanding as of December 31, 2018 $ 7.51  
Weighted-Average Exercise Price, Options granted 21.74  
Weighted-Average Exercise Price, Option exercised 2.61  
Weighted-Average Exercise Price, Outstanding as of March 31, 2019 12.08 $ 7.51
Weighted-Average Exercise Price, Options vested and exercisable as of March 31, 2019 $ 3.20  
Weighted-Average Remaining Contractual Life (Years), Outstanding as of December 31, 2018 9 years 7 months 6 days 9 years 8 months 12 days
Weighted-Average Remaining Contractual Life (Years), Options vested and exercisable as of March 31, 2019 8 years 10 months 24 days  
Aggregate Intrinsic Value, Outstanding as of December 31, 2018 $ 72,708 $ 16,343
Aggregate Intrinsic Value, Options vested and exercisable as of March 31, 2019 $ 2,968