Condensed Consolidated Statements of Comprehensive Loss (Unaudited) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2024	Sep. 30, 2023	Sep. 30, 2024	Sep. 30, 2023
Statement of Comprehensive Income [Abstract]
Net loss	$ (40,158)	$ (55,540)	$ (118,395)	$ (231,366)
Other comprehensive income (loss):
Unrealized income (loss) on marketable securities	1,454	(21)	(600)	994
Total comprehensive loss	(38,704)	(55,561)	(118,995)	(230,372)
Comprehensive loss attributable to noncontrolling interests	0	(12)	(28)	(92)
Comprehensive loss attributable to Zentalis	$ (38,704)	$ (55,549)	$ (118,967)	$ (230,280)