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Related Party Disclosures (Details) - USD ($)
6 Months Ended 12 Months Ended
Jun. 01, 2020
Dec. 21, 2017
Dec. 31, 2021
Dec. 31, 2021
Dec. 31, 2020
Related Party Transaction [Line Items]          
Number of shares acquired (in shares)     0 0 0
Zentera Sublicenses          
Related Party Transaction [Line Items]          
Contra-research and development expense     $ 5,300,000    
Capital Addition Purchase Commitments          
Related Party Transaction [Line Items]          
Equipment purchase and sale agreement $ 400,000        
Affiliated Entity | License Agreement          
Related Party Transaction [Line Items]          
Payments incurred       $ 10,000,000 $ 0
Affiliated Entity | Master Services Agreement          
Related Party Transaction [Line Items]          
Due to related parties     0 0 0
Affiliated Entity | Equipment Purchase and Sale Agreement          
Related Party Transaction [Line Items]          
Due to related parties     0 0 0
Director | Master Services Agreement          
Related Party Transaction [Line Items]          
Due to related parties     $ 1,000,000.0 $ 1,000,000.0 $ 0
VIE, Primary Beneficiary | Kalyra Pharmaceuticals, Inc.          
Related Party Transaction [Line Items]          
Share price (in dollars per share)   $ 0.26      
Cash payments to acquire interest   $ 4,500,000      
Agreement term (in years)       15 years  
VIE, Primary Beneficiary | Series B Preferred Units | Kalyra Pharmaceuticals, Inc.          
Related Party Transaction [Line Items]          
Number of shares acquired (in shares)   17,307,692