(State or Other Jurisdiction of Incorporation) | (Commission File Number) | (IRS Employer Identification No.) | ||||||||||||
(Address of Principal Executive Offices) | (Zip Code) |
Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) | |||||
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) | |||||
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) | |||||
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) |
Title of each class | Trading Symbol(s) | Name of each exchange on which registered | ||||||||||||
Exhibit No. | Description | |||||||
99.1 | ||||||||
104 | Cover Page Interactive Data File (embedded within the Inline XBRL Document) |
ARCUS BIOSCIENCES, INC. | ||||||||
Date: May 23, 2024 | By: | /s/ Terry Rosen, Ph. D. | ||||||
Terry Rosen, Ph.D. | ||||||||
Chief Executive Officer (Principal Executive Officer) |
Efficacy Population | EZFB: E + Z + mFOLFOX-6 ± beva (n=75) | Rego (n=37) | ||||||
Confirmed ORR n (%) [90% CI] | 13 (17.3) [10.6, 26.1] | 1 (2.7) [0.1, 12.2] | ||||||
Median PFS (mo) [95% CI] | 6.2 [5.5, 7.5] | 2.1 [1.8, 3.0] | ||||||
PFS HR [95% CI] | 0.27 [0.17, 0.43] | - | ||||||
Median OS (mo) [95% CI] | 19.7 (14.7, 20.6) | 9.5 (8.0, 12.5) | ||||||
OS HR [95% CI] | 0.37 (0.22, 0.63) | - | ||||||
Safety Population | n=74 | n=35 | ||||||
Grade ≥3 TEAEs n (%) | 61 (82.4) | 17 (48.6) | ||||||
Grade ≥3 related to E or Z or rego n (%) | 17 (23.0) | 9 (25.7) | ||||||
TEAEs leading to discontinuation of all study drugs n (%) | 4 (5.4) | 6 (17.1) |
Cover |
May 23, 2024 |
---|---|
Cover [Abstract] | |
Document Type | 8-K |
Document Period End Date | May 23, 2024 |
Entity Registrant Name | Arcus Biosciences, Inc. |
Entity Incorporation, State or Country Code | DE |
Entity File Number | 001-38419 |
Entity Tax Identification Number | 47-3898435 |
Entity Address, Address Line One | 3928 Point Eden Way |
Entity Address, City or Town | Hayward |
Entity Address, State or Province | CA |
Entity Address, Postal Zip Code | 94545 |
City Area Code | 510 |
Local Phone Number | 694-6200 |
Written Communications | false |
Soliciting Material | false |
Pre-commencement Tender Offer | false |
Pre-commencement Issuer Tender Offer | false |
Title of 12(b) Security | Common Stock, Par Value $0.0001 Per Share |
Trading Symbol | RCUS |
Security Exchange Name | NYSE |
Entity Emerging Growth Company | false |
Amendment Flag | false |
Entity Central Index Key | 0001724521 |
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