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Stock-Based Compensation - Schedule of Assumptions to Estimate Fair Value of Stock Options for Employees and Non-Employees Using Black-Scholes Option Pricing Model (Details) - Options Issued and Outstanding - $ / shares
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Employees        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Fair value of common stock   $ 0.79   $ 0.79
Expected term (in years)   6 years 1 month 6 days   6 years 1 month 6 days
Expected volatility, minimum   74.40%   74.40%
Expected volatility, maximum     77.70% 77.70%
Risk-free interest rate, minimum   1.90%   1.90%
Risk-free interest rate, maximum     2.80% 2.80%
Expected dividend yield 0.00% 0.00% 0.00% 0.00%
Non-employees        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Fair value of common stock   $ 1.00 $ 15.45  
Expected term (in years)   10 years 10 years 10 years
Expected dividend yield   0.00% 0.00% 0.00%
Expected volatility   76.90% 77.90%  
Risk-free interest rate   2.30% 2.70% 2.30%
Minimum | Employees        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Fair value of common stock $ 9.03 $ 0.79 $ 8.57  
Expected term (in years) 5 years 10 months 24 days   5 years 9 months 18 days  
Expected volatility, minimum 89.80%   75.90%  
Risk-free interest rate, minimum 2.80%   2.40%  
Minimum | Non-employees        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Fair value of common stock       $ 0.79
Expected volatility       74.60%
Maximum | Employees        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Fair value of common stock $ 13.94   $ 15.45  
Expected term (in years) 6 years 1 month 6 days   6 years 7 months 6 days  
Expected volatility, minimum 90.60%   90.60%  
Risk-free interest rate, minimum 2.90%   2.90%  
Maximum | Non-employees        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Fair value of common stock       $ 1.00
Expected volatility       76.90%