<SEC-DOCUMENT>0001104659-21-026714.txt : 20210223
<SEC-HEADER>0001104659-21-026714.hdr.sgml : 20210223
<ACCEPTANCE-DATETIME>20210223160545
ACCESSION NUMBER: 0001104659-21-026714
CONFORMED SUBMISSION TYPE: SC 13G/A
PUBLIC DOCUMENT COUNT: 1
FILED AS OF DATE: 20210223
DATE AS OF CHANGE: 20210223
GROUP MEMBERS: NOVARTIS AG
GROUP MEMBERS: NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC.
SUBJECT COMPANY:
COMPANY DATA:
COMPANY CONFORMED NAME: Adicet Bio, Inc.
CENTRAL INDEX KEY: 0001720580
STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834]
IRS NUMBER: 813305277
STATE OF INCORPORATION: DE
FISCAL YEAR END: 1231
FILING VALUES:
FORM TYPE: SC 13G/A
SEC ACT: 1934 Act
SEC FILE NUMBER: 005-90283
FILM NUMBER: 21665379
BUSINESS ADDRESS:
STREET 1: 500 BOYLSTON STREET
STREET 2: 12TH FLOOR
CITY: BOSTON
STATE: MA
ZIP: 02116
BUSINESS PHONE: 617-482-2333
MAIL ADDRESS:
STREET 1: 500 BOYLSTON STREET
STREET 2: 12TH FLOOR
CITY: BOSTON
STATE: MA
ZIP: 02116
FORMER COMPANY:
FORMER CONFORMED NAME: resTORbio, Inc.
DATE OF NAME CHANGE: 20171024
FILED BY:
COMPANY DATA:
COMPANY CONFORMED NAME: Novartis Bioventures Ltd
CENTRAL INDEX KEY: 0001297709
IRS NUMBER: 000000000
STATE OF INCORPORATION: D0
FISCAL YEAR END: 1231
FILING VALUES:
FORM TYPE: SC 13G/A
BUSINESS ADDRESS:
STREET 1: C/O NOVARTIS INTERNATIONAL AG
STREET 2: WSJ-200.220
CITY: CH-4002 BASEL
STATE: V8
ZIP: 0000000000
BUSINESS PHONE: 41-61-324-6210
MAIL ADDRESS:
STREET 1: C/O NOVARTIS INTERNATIONAL AG
STREET 2: WSJ-200.220
CITY: CH-4002 BASEL
STATE: V8
ZIP: 0000000000
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>tm217604d1_sc13g.htm
<DESCRIPTION>SCHEDULE 13GA
<TEXT>
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<HEAD>
<TITLE></TITLE>
</HEAD>
<BODY STYLE="font: 10pt Times New Roman, Times, Serif">
<P STYLE="margin: 0pt"></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center"><B> </B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center"></P>
<!-- Field: Rule-Page --><DIV STYLE="margin-top: 12pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="border-top: Black 2pt solid; border-bottom: Black 1pt solid; font-size: 1pt"> </DIV></DIV><!-- Field: /Rule-Page -->
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center"><B> </B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center"><B>SECURITIES AND EXCHANGE COMMISSION</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center"><B>WASHINGTON, DC 20549</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center"> </P>
<P STYLE="margin: 0pt 0; font-size: 18pt; text-align: center"><B>SCHEDULE 13G </B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center"><FONT STYLE="text-transform: uppercase"><B>Under the Securities
Exchange Act of 1934</B></FONT></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center"><FONT STYLE="text-transform: uppercase"><B>(Amendment No. 3)*</B></FONT></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center"><B> </B></P>
<P STYLE="border-bottom: Black 1pt solid; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><FONT STYLE="font-size: 14pt"><B>Adicet
Bio, Inc.</B></FONT></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">(Name of Issuer)</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center"> </P>
<P STYLE="border-bottom: Black 1pt solid; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>Common
stock, $0.0001 par value per share</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">(Title of Class of Securities)</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center"> </P>
<P STYLE="border-bottom: Black 1pt solid; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>007002108</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">(CUSIP Number)</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center"> </P>
<P STYLE="border-bottom: Black 1pt solid; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>February
16, 2021</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">(Date of Event Which Requires Filing of this Statement)</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">Check the appropriate box to designate the rule pursuant to which
this Schedule is filed:</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"> </P>
<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 1in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Wingdings">¨</FONT></TD><TD STYLE="text-align: justify">Rule
13d-1(b)</TD></TR></TABLE>
<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font-size: 10pt"> </P>
<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 1in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Wingdings">þ</FONT></FONT></TD><TD STYLE="text-align: justify">Rule
13d-1(c)</TD></TR></TABLE>
<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font-size: 10pt"> </P>
<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 1in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Wingdings">¨</FONT></TD><TD STYLE="text-align: justify">Rule
13d-1(d)</TD></TR></TABLE>
<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font-size: 10pt"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left">*The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing
information which would alter the disclosures provided in a prior cover page.</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left">The information required in the remainder of this cover page shall
not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or
otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however,
<I>see</I> the <I>Notes</I>).</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left"></P>
<!-- Field: Rule-Page --><DIV STYLE="margin-top: 3pt; margin-bottom: 12pt; width: 100%"><DIV STYLE="border-top: Black 1pt solid; border-bottom: Black 2pt solid; font-size: 1pt"> </DIV></DIV><!-- Field: /Rule-Page -->
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left"></P>
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<DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="margin: 0pt"> </P></DIV>
<DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt"> </P></DIV>
<!-- Field: /Page -->
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left"> </P>
<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font-size: 10pt; border-collapse: collapse">
<TR STYLE="vertical-align: top">
<TD STYLE="width: 31%; text-align: left; font-size: 10pt"><FONT STYLE="font-size: 10pt"><B><BR STYLE="clear: both">
CUSIP No. 007002108</B></FONT></TD>
<TD STYLE="width: 40%; text-align: center; font-size: 10pt"> </TD>
<TD STYLE="width: 29%; text-align: right; font-size: 10pt"> </TD></TR>
</TABLE>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"> </P>
<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font-size: 10pt; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
<TD STYLE="border-top: black 1pt solid; border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">1.</FONT></TD>
<TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt">Names
of Reporting Persons<BR>
<B>Novartis Bioventures Ltd.</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt"> </P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt; width: 8%"><FONT STYLE="font-size: 10pt">2.</FONT></TD>
<TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt">Check the Appropriate Box
if a Member of a Group (see instructions)</P>
<P STYLE="margin: 0pt 0; font-size: 10pt"> </P></TD>
<TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt; width: 5%"> </TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt"> </TD>
<TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">(a)</FONT></TD>
<TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-family: Wingdings">¨</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"> </TD>
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">(b)</FONT></TD>
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-family: Wingdings">¨</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">3.</FONT></TD>
<TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin-top: 0; margin-bottom: 0"><FONT STYLE="font-size: 10pt">SEC
USE ONLY</FONT></P>
<P STYLE="margin-top: 0; margin-bottom: 0"><FONT STYLE="font-size: 10pt"> </FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">4.</FONT></TD>
<TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt">Citizenship
or Place of Organization</P>
<P STYLE="margin: 0pt 0; font-size: 10pt"><B>Switzerland</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt"><B> </B></P></TD></TR>
</TABLE>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><FONT STYLE="font-size: 1pt"> </FONT></P>
<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font-size: 10pt; width: 100%; border-collapse: collapse">
<TR>
<TD ROWSPAN="4" STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; width: 15%"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">Number
of </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">Shares </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">Beneficially </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">Owned by </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">Each</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">Reporting </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">Person With: </P></TD>
<TD STYLE="border-bottom: black 1pt solid; vertical-align: top; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt; width: 8%"><FONT STYLE="font-size: 10pt">5.</FONT></TD>
<TD STYLE="border-bottom: black 1pt solid; vertical-align: top; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">Sole
Voting Power</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B>0</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B> </B></P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt"><FONT STYLE="font-size: 10pt">6.</FONT></TD>
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">Shared
Voting Power</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B>1,078,116</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B> </B></P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt"><FONT STYLE="font-size: 10pt">7.</FONT></TD>
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">Sole
Dispositive Power</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B>0</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B> </B></P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt"><FONT STYLE="font-size: 10pt">8.</FONT></TD>
<TD STYLE="border-bottom: black 1pt solid"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">Shared
Dispositive Power</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B>1,078,116</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B> </B></P></TD></TR>
</TABLE>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><FONT STYLE="font-size: 1pt"> </FONT></P>
<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font-size: 10pt; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt"><FONT STYLE="font-size: 10pt">9.</FONT></TD>
<TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">Aggregate
Amount Beneficially Owned by Each Reporting Person</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B>1,078,116</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B> </B></P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt; width: 8%"><FONT STYLE="font-size: 10pt">10.</FONT></TD>
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt"><P STYLE="margin-top: 0; margin-bottom: 0"><FONT STYLE="font-size: 10pt">Check
if the Aggregate Amount in Row (9) Excludes Certain Shares (see instructions)</FONT></P>
<P STYLE="margin-top: 0; margin-bottom: 0"><FONT STYLE="font-size: 10pt"> </FONT></P></TD>
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center; font-size: 10pt; width: 5%"><FONT STYLE="font-family: Wingdings">¨</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt"><FONT STYLE="font-size: 10pt">11.</FONT></TD>
<TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">Percent
of Class Represented by Amount in Row 9</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B>3.44%</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B> </B></P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt"><FONT STYLE="font-size: 10pt">12.</FONT></TD>
<TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">Type
of Reporting Person (see instructions)</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B>CO</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B> </B></P></TD></TR>
</TABLE>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"></P>
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<DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="text-align: center; margin-top: 0pt; margin-bottom: 0pt"><FONT STYLE="font-size: 10pt"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->2<!-- Field: /Sequence --></FONT></P></DIV>
<DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt"> </P></DIV>
<!-- Field: /Page -->
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"> </P>
<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font-size: 10pt; border-collapse: collapse">
<TR STYLE="vertical-align: top">
<TD STYLE="width: 31%; text-align: left; font-size: 10pt"><FONT STYLE="font-size: 10pt"><B><BR STYLE="clear: both">
CUSIP No. 007002108</B></FONT></TD>
<TD STYLE="width: 40%; text-align: center; font-size: 10pt"> </TD>
<TD STYLE="width: 29%; text-align: right; font-size: 10pt"> </TD></TR>
</TABLE>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"> </P>
<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font-size: 10pt; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
<TD STYLE="border-top: black 1pt solid; border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">1.</FONT></TD>
<TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt">Names
of Reporting Persons<BR>
<B>Novartis Institutes for BioMedical Research, Inc.</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt"> </P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt; width: 8%"><FONT STYLE="font-size: 10pt">2.</FONT></TD>
<TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt">Check the Appropriate Box
if a Member of a Group (see instructions)</P>
<P STYLE="margin: 0pt 0; font-size: 10pt"> </P></TD>
<TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt; width: 5%"> </TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt"> </TD>
<TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">(a)</FONT></TD>
<TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-family: Wingdings">¨</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"> </TD>
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">(b)</FONT></TD>
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-family: Wingdings">¨</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">3.</FONT></TD>
<TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin-top: 0; margin-bottom: 0"><FONT STYLE="font-size: 10pt">SEC USE ONLY</FONT></P>
<P STYLE="margin-top: 0; margin-bottom: 0"> </P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">4.</FONT></TD>
<TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt">Citizenship
or Place of Organization</P>
<P STYLE="margin: 0pt 0; font-size: 10pt"><B>Delaware</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt"> </P></TD></TR>
</TABLE>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><FONT STYLE="font-size: 1pt"> </FONT></P>
<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font-size: 10pt; width: 100%; border-collapse: collapse">
<TR>
<TD ROWSPAN="4" STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; width: 15%"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">Number
of</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">Shares</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">Beneficially</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">Owned by</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">Each</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">Reporting</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">Person With: </P></TD>
<TD STYLE="border-bottom: black 1pt solid; vertical-align: top; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt; width: 8%"><FONT STYLE="font-size: 10pt">5.</FONT></TD>
<TD STYLE="border-bottom: black 1pt solid; vertical-align: top; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">Sole
Voting Power</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B>0</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B> </B></P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt"><FONT STYLE="font-size: 10pt">6.</FONT></TD>
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">Shared
Voting Power</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B>288,748</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B> </B></P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt"><FONT STYLE="font-size: 10pt">7.</FONT></TD>
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">Sole
Dispositive Power</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B>0</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B> </B></P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt"><FONT STYLE="font-size: 10pt">8.</FONT></TD>
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">Shared
Dispositive Power</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B>288,748 </B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B> </B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B> </B></P></TD></TR>
</TABLE>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><FONT STYLE="font-size: 1pt"> </FONT></P>
<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font-size: 10pt; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt"><FONT STYLE="font-size: 10pt">9.</FONT></TD>
<TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">Aggregate
Amount Beneficially Owned by Each Reporting Person</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B>288,748</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B> </B></P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt; width: 8%"><FONT STYLE="font-size: 10pt">10.</FONT></TD>
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt"><P STYLE="margin-top: 0; margin-bottom: 0"><FONT STYLE="font-size: 10pt">Check
if the Aggregate Amount in Row (9) Excludes Certain Shares (see instructions)</FONT></P>
<P STYLE="margin-top: 0; margin-bottom: 0"><FONT STYLE="font-size: 10pt"> </FONT></P></TD>
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center; font-size: 10pt; width: 5%"><FONT STYLE="font-family: Wingdings">¨</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt"><FONT STYLE="font-size: 10pt">11.</FONT></TD>
<TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">Percent
of Class Represented by Amount in Row 9</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B>0.92%</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B> </B></P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt"><FONT STYLE="font-size: 10pt">12.</FONT></TD>
<TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">Type
of Reporting Person (see instructions)</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B>CO</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B> </B></P></TD></TR>
</TABLE>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"></P>
<!-- Field: Page; Sequence: 3; Value: 2 -->
<DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="text-align: center; margin-top: 0pt; margin-bottom: 0pt"><FONT STYLE="font-size: 10pt"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->3<!-- Field: /Sequence --></FONT></P></DIV>
<DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt"> </P></DIV>
<!-- Field: /Page -->
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"> </P>
<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font-size: 10pt; border-collapse: collapse">
<TR STYLE="vertical-align: top">
<TD STYLE="width: 31%; text-align: left; font-size: 10pt"><FONT STYLE="font-size: 10pt"><B><BR STYLE="clear: both">
CUSIP No. 007002108</B></FONT></TD>
<TD STYLE="width: 40%; text-align: center; font-size: 10pt"> </TD>
<TD STYLE="width: 29%; text-align: right; font-size: 10pt"> </TD></TR>
</TABLE>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"> </P>
<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font-size: 10pt; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
<TD STYLE="border-top: black 1pt solid; border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">1.</FONT></TD>
<TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt">Names
of Reporting Persons<BR>
<B>Novartis AG</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt"> </P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt; width: 8%"><FONT STYLE="font-size: 10pt">2.</FONT></TD>
<TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt">Check the Appropriate Box
if a Member of a Group (see instructions)</P>
<P STYLE="margin: 0pt 0; font-size: 10pt"> </P></TD>
<TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt; width: 5%"> </TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt"> </TD>
<TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">(a)</FONT></TD>
<TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-family: Wingdings">¨</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"> </TD>
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">(b)</FONT></TD>
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-family: Wingdings">¨</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">3.</FONT></TD>
<TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin-top: 0; margin-bottom: 0"><FONT STYLE="font-size: 10pt">SEC
USE ONLY</FONT></P>
<P STYLE="margin-top: 0; margin-bottom: 0"><FONT STYLE="font-size: 10pt"> </FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">4.</FONT></TD>
<TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt">Citizenship
or Place of Organization</P>
<P STYLE="margin: 0pt 0; font-size: 10pt"><B>Switzerland</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt"><B> </B></P></TD></TR>
</TABLE>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><FONT STYLE="font-size: 1pt"> </FONT></P>
<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font-size: 10pt; width: 100%; border-collapse: collapse">
<TR>
<TD ROWSPAN="4" STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; width: 15%"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">Number
of</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">Shares</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">Beneficially</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">Owned by</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">Each</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">Reporting</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center">Person With: </P></TD>
<TD STYLE="border-bottom: black 1pt solid; vertical-align: top; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt; width: 8%"><FONT STYLE="font-size: 10pt">5.</FONT></TD>
<TD STYLE="border-bottom: black 1pt solid; vertical-align: top; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">Sole
Voting Power</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">0</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"> </P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt"><FONT STYLE="font-size: 10pt">6.</FONT></TD>
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">Shared
Voting Power</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B>1,366,864</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B> </B></P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt"><FONT STYLE="font-size: 10pt">7.</FONT></TD>
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">Sole
Dispositive Power</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">0</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"> </P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt"><FONT STYLE="font-size: 10pt">8.</FONT></TD>
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">Shared
Dispositive Power</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B>1,366,864</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B> </B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B> </B></P></TD></TR>
</TABLE>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><FONT STYLE="font-size: 1pt"> </FONT></P>
<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font-size: 10pt; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt"><FONT STYLE="font-size: 10pt">9.</FONT></TD>
<TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">Aggregate
Amount Beneficially Owned by Each Reporting Person</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B>1,366,864</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B> </B></P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt; width: 8%"><FONT STYLE="font-size: 10pt">10.</FONT></TD>
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt"><P STYLE="margin-top: 0; margin-bottom: 0"><FONT STYLE="font-size: 10pt">Check
if the Aggregate Amount in Row (9) Excludes Certain Shares (see instructions)</FONT></P>
<P STYLE="margin-top: 0; margin-bottom: 0"><FONT STYLE="font-size: 10pt"> </FONT></P></TD>
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center; font-size: 10pt; width: 5%"><FONT STYLE="font-family: Wingdings">¨</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt"><FONT STYLE="font-size: 10pt">11.</FONT></TD>
<TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">Percent
of Class Represented by Amount in Row 9</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B>4.36%</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B> </B></P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: justify; font-size: 10pt"><FONT STYLE="font-size: 10pt">12.</FONT></TD>
<TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">Type
of Reporting Person (see instructions)</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B>CO, HC</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"><B> </B></P></TD></TR>
</TABLE>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"></P>
<!-- Field: Page; Sequence: 4; Value: 2 -->
<DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="text-align: center; margin-top: 0pt; margin-bottom: 0pt"><FONT STYLE="font-size: 10pt"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->4<!-- Field: /Sequence --></FONT></P></DIV>
<DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt"> </P></DIV>
<!-- Field: /Page -->
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"> </P>
<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font-size: 10pt; border-collapse: collapse">
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 3.25pt; padding-bottom: 6pt; text-align: left; font-size: 10pt"><B>Item 1(a).</B></TD>
<TD COLSPAN="2" STYLE="padding-right: 5.75pt; padding-left: 5.75pt"><P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"><B>Name
of Issuer: </B></P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"> </P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left">Adicet Bio, Inc.</P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"> </P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 3.25pt; padding-bottom: 6pt; text-align: left; font-size: 10pt"><B>Item 1(b).</B></TD>
<TD COLSPAN="2" STYLE="padding-right: 5.75pt; padding-left: 5.75pt"><P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"><B>Address
of Issuer’s Principal Executive Offices:</B></P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"> </P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left">500 Boylston Street, 13th Floor, Boston, MA 02116</P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"> </P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 3.25pt; padding-bottom: 6pt; text-align: left; font-size: 10pt"><B>Item 2(a).</B></TD>
<TD COLSPAN="2" STYLE="padding-right: 5.75pt; padding-left: 5.75pt"><P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"><B>Name
of Person Filing: </B></P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"> </P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left">This statement is filed on behalf of the following
persons with respect to the shares of Common Stock of the Issuer:</P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"> </P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left">(i) Novartis Bioventures Ltd., a Swiss corporation
(“NBV”), with respect to shares held by it;</P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"> </P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left">(ii) Novartis Institutes for BioMedical Research,
Inc., a Delaware corporation (“NIBRI”), with respect to shares held by it; and</P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"> </P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left">(ii) Novartis AG, a Swiss corporation (“Novartis”),
as the publicly owned parent of NBV and NIBRI, with respect to the shares held by those entities.</P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"> </P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left">The foregoing persons are hereinafter referred to
collectively as the “Reporting Persons.”</P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"> </P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 3.25pt; padding-bottom: 6pt; text-align: left; font-size: 10pt"><B>Item 2(b).</B></TD>
<TD COLSPAN="2" STYLE="padding-right: 5.75pt; padding-left: 5.75pt"><P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"><B>Address
of Principal Business Office or, if none, Residence:</B></P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"> </P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left">The address of the principal business office of
NBV and Novartis is Lichtstrasse 35, 4056 Basel, Switzerland. The address of the principal business office of NIBRI is
250 Massachusetts Avenue, Cambridge, MA 02139.</P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"> </P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 3.25pt; padding-bottom: 6pt; text-align: left; font-size: 10pt"><B>Item 2(c).</B></TD>
<TD COLSPAN="2" STYLE="padding-right: 5.75pt; padding-left: 5.75pt"><P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"><B>Citizenship:</B></P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"> </P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left">NBV is a corporation organized under the laws of
Switzerland and is an indirect wholly-owned subsidiary of Novartis.</P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"> </P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left">NIBRI is a corporation organized under the laws
of Delaware and is an indirect wholly-owned subsidiary of Novartis.</P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"> </P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left">Novartis is a corporation organized under the laws
of Switzerland and is the publicly owned parent of NBV and NIBRI.</P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"> </P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 3.25pt; padding-bottom: 6pt; text-align: left; font-size: 10pt"><B>Item 2(d).</B></TD>
<TD COLSPAN="2" STYLE="padding-right: 5.75pt; padding-left: 5.75pt"><P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"><B>Title
of Class of Securities:</B></P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"> </P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left">Common Stock, par value $0.0001 per share (“Common
Stock”).</P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"> </P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 3.25pt; padding-bottom: 6pt; text-align: left; font-size: 10pt"><B>Item 2(e).</B></TD>
<TD COLSPAN="2" STYLE="padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="margin: 0pt 0.7pt 0pt 0; font-size: 10pt; text-align: left"><B>CUSIP
Number:</B></P>
<P STYLE="margin: 0pt 0.7pt 0pt 0; font-size: 10pt; text-align: left"> </P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left">007002108</P>
<P STYLE="margin: 0pt 0.9pt 0pt 0; font-size: 10pt; text-align: left"> </P></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 3.25pt; padding-left: 5.4pt; text-align: left; font-size: 10pt"><B>Item 3.</B></TD>
<TD COLSPAN="2" STYLE="padding-left: 5.4pt; padding-right: 5.4pt; padding-bottom: 6pt; text-align: left; font-size: 10pt"><B>If this statement
is filed pursuant to §§240.13d-1(b), or 240.13d-2(b) or (c), check whether the person filing is a:</B></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 12.6pt; padding-left: 5.4pt; text-align: right; font-size: 10pt; width: 13%">(a)</TD>
<TD STYLE="text-align: center; font-size: 10pt; width: 0.25in"><FONT STYLE="font-family: Wingdings">¨</FONT></TD>
<TD STYLE="padding-right: 0.9pt; padding-bottom: 6pt; padding-left: 17.1pt; text-align: left; font-size: 10pt; text-indent: -17.1pt">Broker
or dealer registered under Section 15 of the Act (15 U.S.C. 78o);</TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 12.6pt; padding-left: 5.4pt; text-align: right; font-size: 10pt">(b)</TD>
<TD STYLE="text-align: center; font-size: 10pt"><FONT STYLE="font-family: Wingdings">¨</FONT></TD>
<TD STYLE="padding-right: 0.9pt; padding-bottom: 6pt; padding-left: 17.1pt; text-align: left; font-size: 10pt; text-indent: -17.1pt">Bank
as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);</TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 12.6pt; padding-bottom: 6pt; text-align: right; font-size: 10pt">(c)</TD>
<TD STYLE="text-align: center; font-size: 10pt"><FONT STYLE="font-family: Wingdings">¨</FONT></TD>
<TD STYLE="padding-right: 0.9pt; padding-bottom: 6pt; padding-left: 17.1pt; text-align: left; font-size: 10pt; text-indent: -17.1pt">Insurance
company as defined in section 3(a)19) of the Act (15 U.S.C. 78c);</TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 12.6pt; padding-bottom: 6pt; text-align: right; font-size: 10pt">(d)</TD>
<TD STYLE="text-align: center; font-size: 10pt"><FONT STYLE="font-family: Wingdings">¨</FONT></TD>
<TD STYLE="padding-right: 0.9pt; padding-bottom: 6pt; padding-left: 17.1pt; text-align: left; font-size: 10pt; text-indent: -17.1pt">Investment
company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);</TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 12.6pt; padding-bottom: 6pt; text-align: right; font-size: 10pt">(e)</TD>
<TD STYLE="text-align: center; font-size: 10pt"><FONT STYLE="font-family: Wingdings">¨</FONT></TD>
<TD STYLE="padding-right: 0.9pt; padding-bottom: 6pt; padding-left: 17.1pt; text-align: left; font-size: 10pt; text-indent: -17.1pt">An
investment adviser in accordance with §240.13d-1(b)(1)(ii)(E);</TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 12.6pt; text-align: right; font-size: 10pt">(f)</TD>
<TD STYLE="text-align: center; font-size: 10pt"><FONT STYLE="font-family: Wingdings">¨</FONT></TD>
<TD STYLE="padding-right: 0.9pt; padding-left: 17.1pt; text-align: left; font-size: 10pt; text-indent: -17.1pt">An
employee benefit plan or endowment fund in accordance with §240.13d-1(b)(1)(ii)(F);</TD></TR>
</TABLE>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"></P>
<!-- Field: Page; Sequence: 5; Value: 2 -->
<DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="text-align: center; margin-top: 0pt; margin-bottom: 0pt"><FONT STYLE="font-size: 10pt"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->5<!-- Field: /Sequence --></FONT></P></DIV>
<DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt"> </P></DIV>
<!-- Field: /Page -->
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"> </P>
<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font-size: 10pt; border-collapse: collapse">
<TR STYLE="vertical-align: top">
<TD STYLE="width: 13%; padding-right: 12.6pt; padding-bottom: 6pt; text-align: right; font-size: 10pt">(g)</TD>
<TD STYLE="width: 0.25in; text-align: center; font-size: 10pt"><FONT STYLE="font-family: Wingdings">¨</FONT></TD>
<TD STYLE="padding-right: 0.9pt; padding-bottom: 6pt; padding-left: 17.1pt; text-align: left; font-size: 10pt; text-indent: -17.1pt">A
parent holding company or control person in accordance with §240.13d-1(b)(1)(ii)(G);</TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 12.6pt; padding-bottom: 6pt; text-align: right; font-size: 10pt">(h)</TD>
<TD STYLE="text-align: center; font-size: 10pt"><FONT STYLE="font-family: Wingdings">¨</FONT></TD>
<TD STYLE="padding-right: 0.9pt; padding-bottom: 6pt; padding-left: 17.1pt; text-align: left; font-size: 10pt; text-indent: -17.1pt">A
savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);</TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 12.6pt; padding-bottom: 6pt; text-align: right; font-size: 10pt">(i)</TD>
<TD STYLE="text-align: center; font-size: 10pt"><FONT STYLE="font-family: Wingdings">¨</FONT></TD>
<TD STYLE="padding-bottom: 6pt; text-align: left; font-size: 10pt">A church plan that is excluded from the definition of an
investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);</TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 12.6pt; padding-bottom: 6pt; text-align: right; font-size: 10pt">(j)</TD>
<TD STYLE="text-align: center; font-size: 10pt"><FONT STYLE="font-family: Wingdings">¨</FONT></TD>
<TD STYLE="padding-right: 0.9pt; padding-bottom: 6pt; padding-left: 17.1pt; text-align: left; font-size: 10pt; text-indent: -17.1pt">A
non-U.S. institution in accordance with §240.13d–1(b)(1)(ii)(J);</TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 12.6pt; padding-bottom: 6pt; text-align: right; font-size: 10pt">(k)</TD>
<TD STYLE="text-align: center; font-size: 10pt"><FONT STYLE="font-family: Wingdings">¨</FONT></TD>
<TD STYLE="padding-right: 0.9pt; padding-bottom: 6pt; padding-left: 17.1pt; text-align: left; font-size: 10pt; text-indent: -17.1pt">Group,
in accordance with §240.13d–1(b)(1)(ii)(K).</TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 12.6pt; padding-bottom: 6pt; text-align: right; font-size: 10pt"> </TD>
<TD COLSPAN="2" STYLE="padding-right: 5.4pt; padding-bottom: 6pt; padding-left: 5.4pt; text-align: left; font-size: 10pt">If
filing as a non-U.S. institution in accordance with §240.13d–1(b)(1)(ii)(J), please specify the type of institution:
____</TD></TR>
</TABLE>
<P STYLE="margin: 0pt 0.5in; font-size: 10pt; text-align: left; text-indent: -0.5in"> </P>
<TABLE CELLPADDING="0" CELLSPACING="0" BORDER="0" STYLE="width: 100%; margin-top: 0pt; margin-bottom: 0pt; font-size: 10pt">
<TR STYLE="vertical-align: top">
<TD STYLE="text-align: justify; padding-left: 10pt; text-indent: -10pt; width: 13%"><B>Item 4.</B></TD>
<TD STYLE="text-align: justify; padding-left: 10pt; text-indent: -10pt"><B>Ownership</B></TD></TR>
</TABLE>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify; text-indent: 0in"> </P>
<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 7%"></TD><TD STYLE="width: 6%"><B>(a)</B></TD><TD STYLE="text-align: left">Amount Beneficially Owned:</TD></TR></TABLE>
<P STYLE="margin: 0pt 0 0pt 1in; font-size: 10pt; text-align: left; text-indent: 0in"> </P>
<P STYLE="margin: 0pt 0 0pt 1.15in; font-size: 10pt; text-align: left; text-indent: 0in">NBV is the beneficial owner of 1,078,116
shares of Common Stock of the Issuer. NIBRI is the beneficial owner of 288,748 shares of Common Stock of the Issuer. As the indirect
parent of NBV and NIBRI, Novartis may be deemed to beneficially own these securities. Each of NBV and NIBRI expressly disclaim
beneficial ownership of shares beneficially owned by the other entity. </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify; text-indent: 0.5in"> </P>
<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 7%"></TD><TD STYLE="width: 6%"><B>(b)</B></TD><TD STYLE="text-align: left">Percent of Class:</TD></TR></TABLE>
<P STYLE="margin: 0pt 0 0pt 1in; font-size: 10pt; text-align: left; text-indent: 0in"> </P>
<P STYLE="margin: 0pt 0 0pt 1.15in; font-size: 10pt; text-align: left; text-indent: 0in">NBV, NIBRI and Novartis beneficially
own 3.44%, 0.92% and 4.36%, respectively, of the Issuer’s outstanding Common Stock. The percentages used in this Schedule
13G/A were calculated based upon 31,318,990 shares of Common Stock of the Issuer outstanding, as reported in the Issuer’s
prospectus filed pursuant to Rule 424(b)(5) with the Securities and Exchange Commission on February 11, 2021 and the Issuer’s
press release issued February 16, 2021, after giving effect to the completion of the public offering and concurrent private offering,
and the full exercise of the underwriters’ over-allotment option in the public offering, all as described therein.</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify; text-indent: 0.5in"> </P>
<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 7%"></TD><TD STYLE="width: 6%"><B>(c)</B></TD><TD STYLE="text-align: left">Number of shares as to which the
person has:</TD></TR></TABLE>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify; text-indent: 0.5in"> </P>
<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 13%"></TD><TD STYLE="width: 0.5in"><B>(i)</B></TD><TD STYLE="text-align: left">Sole power to vote or to direct
the vote: Not applicable as to each Reporting Person.	</TD></TR></TABLE>
<P STYLE="margin: 0pt 0 0pt 1.5in; font-size: 10pt; text-align: left; text-indent: 0.5in"> </P>
<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 13%"></TD><TD STYLE="width: 0.5in"><B>(ii)</B></TD><TD STYLE="text-align: justify">Shared power to vote or to
direct the vote: please see row 6 of the cover sheet to this Schedule 13G for each Reporting
Person, which information is incorporated herein by reference.</TD></TR></TABLE>
<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font-size: 10pt"> </P>
<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 13%"></TD><TD STYLE="width: 0.5in"><B>(iii)</B></TD><TD STYLE="text-align: justify">Sole power to dispose or
to direct the disposition of: Not applicable as to each Reporting Person.</TD></TR></TABLE>
<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font-size: 10pt"> </P>
<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 13%"></TD><TD STYLE="width: 0.5in"><B>(iv)</B></TD><TD STYLE="text-align: justify">Shared power to dispose or
to direct the disposition of: please see row 8 of the cover sheet to this Schedule 13G
for each Reporting Person, which information is incorporated herein by reference.</TD></TR></TABLE>
<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font-size: 10pt"> </P>
<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font-size: 10pt"></P>
<!-- Field: Page; Sequence: 6; Value: 2 -->
<DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="text-align: center; margin-top: 0pt; margin-bottom: 0pt"><FONT STYLE="font-size: 10pt"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->6<!-- Field: /Sequence --></FONT></P></DIV>
<DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt"> </P></DIV>
<!-- Field: /Page -->
<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font-size: 10pt"> </P>
<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 13%"><B>Item 5.</B></TD><TD STYLE="text-align: left"><B>Ownership of 5 Percent or Less of a Class</B></TD></TR></TABLE>
<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font-size: 10pt"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left; text-indent: 0in">If this statement is being filed to report the fact
that as of the date hereof the reporting person has ceased to be the beneficial owner of more than 5 percent of the class of securities,
check the following <FONT STYLE="font-family: Wingdings">þ</FONT></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left; text-indent: 0in"> </P>
<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 13%"><B>Item 6.</B></TD><TD STYLE="text-align: left"><B>Ownership of More than 5 Percent on Behalf of Another
Person</B></TD></TR></TABLE>
<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font-size: 10pt"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left; text-indent: 0in">Not Applicable</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left; text-indent: 0in"> </P>
<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 13%"><B>Item 7.</B></TD><TD STYLE="text-align: left"><B>Identification and Classification of the Subsidiary
Which Acquired the Security Being Reported on By the Parent Holding Company or Control
Person.</B></TD></TR></TABLE>
<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font-size: 10pt"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left; text-indent: 0in">Not Applicable</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left; text-indent: 0in"> </P>
<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 13%"><B>Item 8.</B></TD><TD STYLE="text-align: left"><B>Identification and Classification of Members of the
Group</B></TD></TR></TABLE>
<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font-size: 10pt"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left; text-indent: 0in">Not Applicable</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left; text-indent: 0in"> </P>
<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 13%"><B>Item 9.</B></TD><TD STYLE="text-align: left"><B>Notice of Dissolution of a Group</B></TD></TR></TABLE>
<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font-size: 10pt"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left; text-indent: 0in">Not Applicable</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left; text-indent: 0in"> </P>
<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 13%"><B>Item 10.</B></TD><TD STYLE="text-align: left"><B>Certification</B></TD></TR></TABLE>
<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font-size: 10pt"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left">Each of the Reporting Persons hereby makes the following certification:</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left">By signing below I certify that, to the best of my knowledge and belief,
the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing
the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any
transaction having that purpose or effect.</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left"></P>
<!-- Field: Page; Sequence: 7; Value: 2 -->
<DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="text-align: center; margin-top: 0pt; margin-bottom: 0pt"><FONT STYLE="font-size: 10pt"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->7<!-- Field: /Sequence --></FONT></P></DIV>
<DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt"> </P></DIV>
<!-- Field: /Page -->
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center"><B>Signatures</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left">After reasonable inquiry and to the best of my knowledge and belief,
I certify that the information set forth in this statement is true, complete and correct.</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left"> </P>
<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 100%">
<TR STYLE="vertical-align: bottom">
<TD STYLE="font-size: 10pt; width: 50%">Date: February 23, 2021</TD>
<TD STYLE="font-size: 10pt; width: 50%"> </TD></TR>
<TR STYLE="vertical-align: bottom">
<TD STYLE="font-size: 10pt; font-variant: small-caps"> </TD>
<TD STYLE="font-size: 10pt; font-variant: small-caps">Novartis Bioventures Ltd.</TD></TR>
<TR STYLE="vertical-align: bottom">
<TD COLSPAN="2" STYLE="font-size: 10pt; font-variant: small-caps; font-weight: bold"> </TD></TR>
<TR STYLE="vertical-align: bottom">
<TD STYLE="font-size: 10pt"> </TD>
<TD STYLE="border-bottom: Black 1pt solid; font-size: 10pt">/s/ Bart Dzikowski</TD></TR>
<TR STYLE="vertical-align: bottom">
<TD STYLE="font-size: 10pt"> </TD>
<TD STYLE="font-size: 10pt">Name: Bart Dzikowski</TD></TR>
<TR STYLE="vertical-align: bottom">
<TD STYLE="font-size: 10pt"> </TD>
<TD STYLE="font-size: 10pt">Title: Secretary of the Board</TD></TR>
<TR STYLE="vertical-align: bottom">
<TD COLSPAN="2" STYLE="font-size: 10pt"> </TD></TR>
<TR STYLE="vertical-align: bottom">
<TD STYLE="font-size: 10pt"> </TD>
<TD STYLE="border-bottom: Black 1pt solid; font-size: 10pt">/s/ Beat Steffen</TD></TR>
<TR STYLE="vertical-align: bottom">
<TD STYLE="font-size: 10pt"> </TD>
<TD STYLE="font-size: 10pt">Name: Beat Steffen</TD></TR>
<TR STYLE="vertical-align: bottom">
<TD STYLE="font-size: 10pt"> </TD>
<TD STYLE="font-size: 10pt">Title: Authorized Signatory</TD></TR>
<TR STYLE="vertical-align: bottom">
<TD COLSPAN="2" STYLE="font-size: 10pt; font-variant: small-caps; font-weight: bold"> </TD></TR>
<TR STYLE="vertical-align: bottom">
<TD STYLE="font-size: 10pt; font-variant: small-caps"> </TD>
<TD STYLE="font-size: 10pt; font-variant: small-caps">Novartis Institutes for</TD></TR>
<TR STYLE="vertical-align: bottom">
<TD STYLE="font-size: 10pt; font-variant: small-caps"> </TD>
<TD STYLE="font-size: 10pt; font-variant: small-caps">BioMedical Research, Inc.</TD></TR>
<TR STYLE="vertical-align: bottom">
<TD COLSPAN="2" STYLE="font-size: 10pt; font-variant: small-caps"> </TD></TR>
<TR STYLE="vertical-align: bottom">
<TD STYLE="font-size: 10pt"> </TD>
<TD STYLE="border-bottom: Black 1pt solid; font-size: 10pt">/s/ Scott A. Brown</TD></TR>
<TR STYLE="vertical-align: bottom">
<TD STYLE="font-size: 10pt"> </TD>
<TD STYLE="font-size: 10pt">Name: Scott A. Brown</TD></TR>
<TR STYLE="vertical-align: bottom">
<TD STYLE="font-size: 10pt"> </TD>
<TD STYLE="font-size: 10pt">Title: General Counsel and Chief Administrative Officer</TD></TR>
<TR STYLE="vertical-align: bottom">
<TD COLSPAN="2" STYLE="font-size: 10pt"> </TD></TR>
<TR STYLE="vertical-align: bottom">
<TD STYLE="font-size: 10pt; font-variant: small-caps"> </TD>
<TD STYLE="font-size: 10pt; font-variant: small-caps">Novartis AG</TD></TR>
<TR STYLE="vertical-align: bottom">
<TD COLSPAN="2" STYLE="font-size: 10pt"> </TD></TR>
<TR STYLE="vertical-align: bottom">
<TD STYLE="font-size: 10pt"> </TD>
<TD STYLE="border-bottom: Black 1pt solid; font-size: 10pt">/s/ Bart Dzikowski</TD></TR>
<TR STYLE="vertical-align: bottom">
<TD STYLE="font-size: 10pt"> </TD>
<TD STYLE="font-size: 10pt">Name: Bart Dzikowski</TD></TR>
<TR STYLE="vertical-align: bottom">
<TD STYLE="font-size: 10pt"> </TD>
<TD STYLE="font-size: 10pt">Title: Authorized Signatory</TD></TR>
<TR STYLE="vertical-align: bottom">
<TD COLSPAN="2" STYLE="font-size: 10pt"> </TD></TR>
<TR STYLE="vertical-align: bottom">
<TD STYLE="font-size: 10pt"> </TD>
<TD STYLE="border-bottom: Black 1pt solid; font-size: 10pt">/s/ Beat Steffen</TD></TR>
<TR STYLE="vertical-align: bottom">
<TD STYLE="font-size: 10pt"> </TD>
<TD STYLE="font-size: 10pt">Name: Beat Steffen</TD></TR>
<TR STYLE="vertical-align: bottom">
<TD STYLE="font-size: 10pt"> </TD>
<TD STYLE="font-size: 10pt">Title: Authorized Signatory</TD></TR>
</TABLE>
<P STYLE="margin: 0pt 0.75in 0pt 3in; font-size: 10pt; text-align: justify"> </P>
<P STYLE="margin: 0pt 0.75in 0pt 3in; font-size: 10pt; text-align: justify"></P>
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<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center"><B>EXHIBIT INDEX</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center"><B> </B></P>
<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font-size: 10pt; border-collapse: collapse">
<TR STYLE="vertical-align: top">
<TD STYLE="white-space: nowrap; width: 13%; padding-right: 5.4pt; padding-left: 5.4pt; text-align: left; font-size: 10pt"><U>Exhibit
Number</U></TD>
<TD STYLE="padding-bottom: 1pt; width: 2%"> </TD>
<TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt; text-align: left; font-size: 10pt"><U>Exhibit Description</U></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt; text-align: left; font-size: 10pt">4</TD>
<TD> </TD>
<TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt; text-align: left; font-size: 10pt">Joint Filing Agreement</TD></TR>
</TABLE>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left"></P>
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<DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt"> </P></DIV>
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<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: left"><B> </B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center"><B>EXHIBIT 4</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center"><B> </B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center"><B>Joint Filing Agreement</B></P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: center"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">In accordance with Rule 13d-1(k) under the Securities Exchange
Act of 1934, as amended, the undersigned agree to the joint filing on behalf of each of them of a Statement on Schedule 13G
(including amendments thereto) with respect to the common stock, $0.0001 par value per share, of Adicet Bio, Inc., a Delaware
corporation, and further agree that this Joint Filing Agreement shall be included as an exhibit to such joint filings.</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">The undersigned further agree that each party hereto is responsible
for the timely filing of such Schedule 13G and any amendments thereto, and for the completeness and accuracy of the information
concerning such party contained therein; <U>provided</U> that no party is responsible for the completeness or accuracy of the
information concerning any other filing party, unless such party knows or has reason to believe that such information is inaccurate.</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">This Joint Filing Agreement may be executed in one or more counterparts,
each of which shall be deemed to be an original instrument, but all of such counterparts together shall constitute one agreement.</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify">In evidence thereof, the undersigned, being duly authorized, hereby
execute this Joint Filing Agreement as of February 23, 2021.</P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"> </P>
<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 100%">
<TR STYLE="vertical-align: bottom">
<TD STYLE="font-size: 10pt; width: 50%"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="font-size: 10pt; font-variant: small-caps; width: 50%"><FONT STYLE="font-size: 10pt">Novartis Bioventures Ltd.</FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="font-size: 10pt; font-variant: small-caps; font-weight: bold"><FONT STYLE="font-size: 10pt"> </FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="border-bottom: Black 1pt solid; font-size: 10pt"><FONT STYLE="font-size: 10pt">/s/ Bart Dzikowski</FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Name: Bart Dzikowski</FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Title: Secretary of the Board</FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="border-bottom: Black 1pt solid; font-size: 10pt"><FONT STYLE="font-size: 10pt">/s/ Beat Steffen</FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Name: Beat Steffen</FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Title: Authorized Signatory</FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="font-size: 10pt; font-variant: small-caps"><FONT STYLE="font-size: 10pt">Novartis Institutes for</FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="font-size: 10pt; font-variant: small-caps"><FONT STYLE="font-size: 10pt">BioMedical Research, Inc.</FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="font-size: 10pt; font-variant: small-caps"><FONT STYLE="font-size: 10pt"> </FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="border-bottom: Black 1pt solid; font-size: 10pt"><FONT STYLE="font-size: 10pt">/s/ Scott A. Brown</FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Name: Scott A. Brown</FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Title: General Counsel and Chief Administrative Officer</FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="font-size: 10pt; font-variant: small-caps"><FONT STYLE="font-size: 10pt">Novartis AG</FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="border-bottom: Black 1pt solid; font-size: 10pt"><FONT STYLE="font-size: 10pt">/s/ Bart Dzikowski</FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Name: Bart Dzikowski</FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Title: Authorized Signatory</FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="border-bottom: Black 1pt solid; font-size: 10pt"><FONT STYLE="font-size: 10pt">/s/ Beat Steffen</FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Name: Beat Steffen</FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: bottom">
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"> </FONT></TD>
<TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Title: Authorized Signatory</FONT></TD></TR>
</TABLE>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"> </P>
<P STYLE="margin: 0pt 0; font-size: 10pt; text-align: justify"></P>
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