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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Cash flows from operating activities    
Net income (loss) $ (17,920) $ (32,173)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization expense 757 785
Noncash lease expense 1,304 1,377
Stock-based compensation expense 8,685 5,702
Net amortization of premiums and accretion discounts on investments 0 10
Loss on disposal of property and equipment 18 0
Amortization of deferred debt issuance costs 18 100
Impairment of in-process research and development 0 1,190
Remeasurement of contingent consideration liability 0 (980)
Changes in operating assets and liabilities:    
Accounts receivable - related party 185 0
Prepaid expenses and other current assets 1,280 (1,240)
Other non-current assets 408 (116)
Accounts payable (1,186) 764
Contract liabilities — related party (4,805) (833)
Operating lease liabilities (902) (1,098)
Accrued and other current and non-current liabilities 1,558 (1,412)
Net cash used in operating activities (10,600) (27,924)
Cash flows from investing activities    
Proceeds from sales of marketable debt securities 0 7,500
Proceeds from maturities of marketable debt securities 0 2,750
Purchases of property and equipment (5,481) (2,790)
Net cash provided by (used in) investing activities (5,481) 7,460
Cash flows from financing activities    
Proceeds from issuance of common stock, net of issuance costs 0 143,754
Proceeds from Employee Stock Purchase Plan 203 0
Proceeds from exercise of stock options 277 1,255
Taxes withheld and paid related to net share settlement of equity awards (1,106) 0
Deferred issuance costs (345) (149)
Net cash provided by (used in) financing activities (971) 144,860
Net change in cash, cash equivalents and restricted cash (17,052) 124,396
Cash, cash equivalents and restricted cash, at the beginning of period 277,694 88,857
Cash, cash equivalents and restricted cash, at the end of period 260,642 213,253
Reconciliation of cash, cash equivalents and restricted cash:    
Cash and cash equivalents 260,642 208,726
Restricted cash 0 4,527
Cash, cash equivalents and restricted cash, at the end of period 260,642 213,253
Supplemental cash flow information    
Cash received from tax refund 0 158
Supplemental disclosures of noncash investing and financing activities    
Purchases of property and equipment included in accounts payable 4,469 1,363
Operating right-of-use assets obtained in exchange for operating lease liabilities 2,343 0
Adjustment to goodwill $ 0 $ 413