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Collaboration Agreements - Sanofi (Details) - USD ($)
3 Months Ended 9 Months Ended 60 Months Ended
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Dec. 31, 2022
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]            
Collaboration revenue from customers [1] $ 1,267,000 $ 184,000 $ 330,531,000 $ 94,805,000    
Sanofi | Collaborative Arrangement            
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]            
Contract liability 0   0   $ 0 $ 0
Transaction price, increase (decrease) 0 0 $ 25,000,000 $ 40,000,000    
Collaboration revenue from customers $ 0 $ 0        
Sanofi | Collaborative Arrangement | Milestone Triggered            
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]            
Collaboration revenue from customers         100,000,000  
Sanofi | Collaborative Arrangement | Product            
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]            
Collaboration revenue from customers         $ 0  
[1] Includes related-party collaboration revenue from customers of $1.3 million and $295.5 million for the three and nine months ended September 30, 2023, respectively, and $0.2 million and $2.9 million for the three and nine months ended September 30, 2022, respectively.