Commitments and Contingencies - Narrative (Details)	3 Months Ended		6 Months Ended
	Jun. 30, 2023 USD ($)	Jun. 30, 2022 USD ($)	Jun. 30, 2023 USD ($)	Jun. 30, 2022 USD ($)	Apr. 30, 2023 USD ($) ft²	Apr. 12, 2023	Dec. 31, 2022 USD ($)
Loss Contingencies [Line Items]
Operating lease cost	$ 3,300,000	$ 2,600,000	$ 6,200,000	$ 5,500,000
DMSA, Non-Cancellable
Loss Contingencies [Line Items]
Purchase commitments	41,500,000		41,500,000				$ 32,300,000
DMSA
Loss Contingencies [Line Items]
Costs incurred	10,900,000	9,500,000	16,100,000	19,500,000
Payments for development and manufacturing services	8,300,000	$ 7,000,000	12,100,000	$ 15,700,000
Other than DMSA
Loss Contingencies [Line Items]
Purchase commitments	39,300,000		39,300,000				$ 9,600,000
Building | SLC Lease
Loss Contingencies [Line Items]
Lease not yet commenced, lease liability	0		0
Lease not yet commenced, ROU asset	0		0
Lease not yet commenced, operating lease expense			0
Building | SLC Lease | Operating Lease, 9.3 Year Lease Agreement, Terminated
Loss Contingencies [Line Items]
Accelerated depreciation on leasehold improvements in relation to SLC Lease termination			7,900,000
Laboratory, Office, and Warehouse | New SLC Operating Lease | Operating Lease, 15 Year Lease Agreement
Loss Contingencies [Line Items]
Lease not yet commenced, lease liability	0		0
Lease not yet commenced, ROU asset	0		0
Lease not yet commenced, operating lease expense	$ 0		$ 0
Lease not yet commenced, area under lease | ft²					59,336
Lease not yet commenced, period						15 years
Lease not yet commenced, undiscounted lease payments					$ 13,400,000