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Collaborations - Additional Information (Detail) - USD ($)
3 Months Ended 9 Months Ended 12 Months Ended
Oct. 22, 2020
Mar. 31, 2023
Mar. 31, 2022
Sep. 30, 2022
Dec. 31, 2022
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]          
Related party revenue recognized     $ 1,925,000    
Ultragenyx [Member] | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement [Member]          
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]          
Milestone payments upon achievement of regulatory milestone   $ 65,000,000      
Percentage of option to fund of development cost   30.00%      
Percentage of net income and net losses on net sales   30.00%      
Agreement termination notice period   90 days      
Issued and sold shares of common stock 521,719        
Common stock issued price per share $ 76.6695        
Proceeds from issuance of common stock, net of issuance costs $ 40,000,000        
Percentage of outstanding common stock 14.45% 2.70%      
Transaction price determined under ASC 606   $ 22,513,000      
Transaction price   0      
Related party revenue recognized   0 $ 1,925,000   $ 0
Deferred revenue - related party   0     $ 0
Ultragenyx [Member] | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement [Member] | Maximum [Member]          
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]          
Milestone payments upon achievement of development milestone   25,000,000      
Milestone Payments upon achievement of net sales milestones   $ 165,000,000      
Ultragenyx [Member] | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement [Member] | Minimum [Member]          
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]          
Percentage of outstanding common stock       10.00%