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Stock-Based Awards - Summary of Stock-based Compensation Expense (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Total stock-based compensation $ 26,944 $ 24,814 $ 83,044 $ 77,217
Research and development        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Total stock-based compensation 15,819 12,607 46,284 39,791
Selling, general and administrative        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Total stock-based compensation $ 11,125 $ 12,207 $ 36,760 $ 37,426