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Organization - Additional Information (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended
Jul. 10, 2020
Nov. 30, 2020
Mar. 31, 2021
Dec. 31, 2020
Organization Consolidation And Presentation Of Financial Statements [Line Items]        
Common stock price per share     $ 0.0001 $ 0.0001
Accumulated deficit     $ 836,095 $ 667,184
Cash, cash equivalents and short-term investments     $ 733,000  
Common Stock | Sales Agreement        
Organization Consolidation And Presentation Of Financial Statements [Line Items]        
Issuance of common stock, shares     0  
Common stock price per share   $ 0.0001    
Common Stock | Sales Agreement | Maximum        
Organization Consolidation And Presentation Of Financial Statements [Line Items]        
Percentage of aggregate gross proceeds from sale of shares   3.00%    
Aggregate offering price   $ 300,000    
Follow-on Offering | Common Stock        
Organization Consolidation And Presentation Of Financial Statements [Line Items]        
Issuance of common stock, shares 8,214,285      
Common stock price per share $ 42.00      
Gross proceeds from the offering $ 345,000      
Payments of underwriting discounts and commissions 20,700      
Offering expenses 1,100      
Net proceeds after deducting underwriting discounts, commissions and offering expenses $ 323,200