Selected Quarterly Financial Data (Unaudited) - Schedule of Selected Quarterly Financial Data (Unaudited) (Details) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended								12 Months Ended
	Dec. 31, 2020	Sep. 30, 2020	Jun. 30, 2020	Mar. 31, 2020	Dec. 31, 2019	Sep. 30, 2019	Jun. 30, 2019	Mar. 31, 2019	Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2018
Quarterly Financial Information Disclosure [Abstract]
Total revenue	$ 1,734	$ 1,928	$ 66,988	$ 5,718	$ 980	$ 1,403	$ 2,047	$ 3,661	$ 76,368	$ 8,091	$ 10,668
Total operating expenses	(110,138)	(89,543)	(96,039)	(77,628)	(64,739)	(49,083)	(37,817)	(34,431)	(373,348)	(186,070)	(129,360)
Net loss	$ (105,649)	$ (84,609)	$ (31,167)	$ (77,240)	$ (63,771)	$ (48,314)	$ (33,928)	$ (28,670)	$ (298,665)	$ (174,683)	$ (115,884)
Net loss per share, basic	$ (0.83)	$ (0.67)	$ (0.27)	$ (0.71)	$ (0.69)	$ (4.60)	$ (3.64)	$ (3.19)
Net loss per share, diluted	$ (0.83)	$ (0.67)	$ (0.27)	$ (0.71)	$ (0.71)	$ (4.60)	$ (3.64)	$ (3.19)