The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
2SEVENTY BIO INC COMMON STOCK 901384107 4,598 179,393 SH   SOLE   179,393 0 0
ADAGIO THERAPEUTICS INC COM 00534A102 14,064 1,937,207 SH   SOLE   1,937,207 0 0
AEGLEA BIOTHERAPEUTICS INC COM 00773J103 13,527 2,847,689 SH   SOLE   2,847,689 0 0
ANNEXON INC COM 03589W102 37,246 3,241,628 SH   SOLE   3,241,628 0 0
APTINYX INC COM 03836N103 23,741 8,891,758 SH   SOLE   8,891,758 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 82,531 3,979,292 SH   SOLE   3,979,292 0 0
ARYA SCIENCES ACQU CORP IV CL A G31659108 6,941 700,000 SH   SOLE   700,000 0 0
ARYA SCIENCES ACQUISITN CORP CLASS A ORD SHS G31658100 4,850 500,000 SH   SOLE   500,000 0 0
ATEA PHARMACEUTICALS INC COM 04683R106 22,222 2,485,638 SH   SOLE   2,485,638 0 0
BCLS ACQUISITION CORP COM CL A G0904B105 4,778 487,500 SH   SOLE   487,500 0 0
BLUEBIRD BIO INC COM 09609G100 5,376 538,179 SH   SOLE   538,179 0 0
C4 THERAPEUTICS INC COM STK 12529R107 52,879 1,642,210 SH   SOLE   1,642,210 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 57,664 2,029,701 SH   SOLE   2,029,701 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 118,399 8,415,000 SH   SOLE   8,415,000 0 0
EQRX INC COM 26886C107 68,224 10,003,573 SH   SOLE   10,003,573 0 0
FRAZIER LIFESCIENCES ACQU CO UNIT 12/09/2025 G3710A121 2,976 300,000 SH   SOLE   300,000 0 0
JIYA ACQUISITION CORP COM CL A 47760M102 2,931 300,000 SH   SOLE   300,000 0 0
MARINUS PHARMACEUTICALS INC COM NEW 56854Q200 17,001 1,431,058 SH   SOLE   1,431,058 0 0
MERSANA THERAPEUTICS INC COM 59045L106 33,499 5,385,667 SH   SOLE   5,385,667 0 0
NAUTILUS BIOTECHNOLOGY INC COM 63909J108 10,360 2,000,000 SH   SOLE   2,000,000 0 0
NURIX THERAPEUTICS INC COM 67080M103 37,181 1,284,313 SH   SOLE   1,284,313 0 0
NUVALENT INC COM 670703107 65,269 3,428,014 SH   SOLE   3,428,014 0 0
OMEGA ALPHA SPAC CL A G6749V107 3,908 400,000 SH   SOLE   400,000 0 0
PANACEA ACQUISITION CORP II CL A SHS G6882C106 4,850 500,000 SH   SOLE   500,000 0 0
PHARVARIS N V COM N69605108 45,769 3,180,601 SH   SOLE   3,180,601 0 0
RAPID MICRO BIOSYSTEMS INC CLASS A COM 75340L104 89,744 8,434,560 SH   SOLE   8,434,560 0 0
RESEARCH ALLIANCE CORP II COM CL A 760873109 9,770 1,000,000 SH   SOLE   1,000,000 0 0
SAVARA INC COM 805111101 14,412 11,622,598 SH   SOLE   11,622,598 0 0
SOLID BIOSCIENCES INC COM 83422E105 13,877 7,929,918 SH   SOLE   7,929,918 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107 299,444 4,831,307 SH   SOLE   4,831,307 0 0
SYROS PHARMACEUTICALS INC COM 87184Q107 20,422 6,264,420 SH   SOLE   6,264,420 0 0
TANGO THERAPEUTICS INC COM 87583X109 21,024 1,921,790 SH   SOLE   1,921,790 0 0
X4 PHARMACEUTICALS INC COM 98420X103 6,610 2,886,542 SH   SOLE   2,886,542 0 0
XILIO THERAPEUTICS INC COM 98422T100 44,887 2,805,413 SH   SOLE   2,805,413 0 0