Note 10 - Share-based Compensation - Summary of Stock Option Activity (Details) $ / shares in Units, $ in Thousands	9 Months Ended	12 Months Ended
	Sep. 30, 2022 USD ($) $ / shares shares	Dec. 31, 2021 $ / shares shares
Options on Common Shares, Outstanding (in shares) | shares	3,935,883
Outstanding, weighted average exercise price (in dollars per share) | $ / shares	$ 5.24
Outstanding, remaining contractual term (Year)	6 years 3 days	4 years 9 months 14 days
Options on Common Shares, Granted (in shares) | shares	2,734,639
Granted, weighted average exercise price (in dollars per share) | $ / shares	$ 2.85
Options on Common Shares, Exercised (in shares) | shares	(55,500)
Exercised, weighted average exercise price (in dollars per share) | $ / shares	$ 1.50
Options on Common Shares, Forfeited, cancelled, expired (in shares) | shares	(978,709)
Forfeited, cancelled, expired, weighted average exercise price (in dollars per share) | $ / shares	$ 5.48
Outstanding September 30, 2022 (in shares) | shares	5,636,313	3,935,883
Outstanding, weighted average exercise price (in dollars per share) | $ / shares	$ 3.74	$ 5.24
Outstanding September 30, 2022 | $	$ 232,778
Exercisable September 30, 2022 (in shares) | shares	2,507,744
Exercisable weighted average exercise price (in dollars per share) | $ / shares	$ 4.47
Exercisable, remaining contractual term (Year)	2 years 1 month 20 days
Exercisable September 30, 2022 | $	$ 232,778