STOCK-BASED COMPENSATION (Tables)

3 Months Ended

Mar. 31, 2023

Share-Based Payment Arrangement [Abstract]

Schedule of Stock-Based Compensation

The Company recorded stock-based compensation expense in the following award type categories included within the condensed consolidated statements of operations and comprehensive loss:

	Three Months Ended March 31,
	2023		2022
Stock options	$	2,455	$	3,193
Restricted stock units	112		121
Employee Stock Purchase Plan and Other	104		61
	$	2,671	$	3,375

The Company recorded stock-based compensation expense in the following expense categories of its condensed consolidated statements of operations and comprehensive loss:

	Three Months Ended March 31,
	2023		2022
Research and development	$	949	$	1,528
General and administrative	1,722		1,847
	$	2,671	$	3,375

Schedule of Stock Option Activity

The following table summarizes the stock option activity under the Company’s equity awards plans:

	Options	Weighted Average Exercise Price		Weighted Average Remaining Life (in Years)	Intrinsic Value (in thousands)
Outstanding December 31, 2022	5,359,400	$	12.40	7.8	$	76
Granted	2,659,250	$	2.90
Cancelled or forfeited	(240,241)	$	11.15
Expired	(68,124)	$	28.26
Outstanding March 31, 2023	7,710,285	$	9.02	8.4	$	116
Options vested or expected to vest at March 31, 2023	7,710,285	$	9.02	8.4	$	116
Options exercisable at March 31, 2023	2,828,178	$	14.41	7.0	$	32

Schedule of Restricted Stock Activity

The following table summarizes time-based restricted stock activity since January 1, 2023:

	Number of shares	Weighted average grant date fair value
Unvested restricted common stock as of December 31, 2022	101,397	$	5.92
Vested	(13,959)	$	14.53
Cancelled or forfeited	(1,148)	$	2.14
Unvested restricted common stock as of March 31, 2023	86,290	$	4.57