Fair value inputs probability of funding.

No definition available.

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- Definition

Fair value, after the effects of master netting arrangements, of a financial liability or contract with one or more underlyings, notional amount or payment provision or both, and the contract can be net settled by means outside the contract or delivery of an asset. Includes liabilities not subject to a master netting arrangement and not elected to be offset.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 20
-Section 50
-Paragraph 3
-Subparagraph (c)
-URI http://asc.fasb.org/extlink&oid=51824906&loc=SL20225862-175312

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 825
-SubTopic 10
-Section 50
-Paragraph 10
-URI http://asc.fasb.org/extlink&oid=109250915&loc=d3e13433-108611

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 20
-Section 55
-Paragraph 10
-URI http://asc.fasb.org/extlink&oid=99393222&loc=SL20226008-175313

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

+ Details

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- Definition

Amount of transfers of assets measured on a recurring basis out of Level 1 of the fair value hierarchy into Level 2.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 820
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (bb)
-URI http://asc.fasb.org/extlink&oid=99377789&loc=d3e19207-110258

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- Definition

Amount of transfers of assets measured on a recurring basis out of Level 2 of the fair value hierarchy into Level 1.

+ References

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- Definition

Amount of transfers of liabilities measured on a recurring basis out of Level 1 of the fair value hierarchy into Level 2.

+ References

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- Definition

Amount of transfers of liabilities measured on a recurring basis out of Level 2 of the fair value hierarchy into Level 1.

+ References

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- Definition

Amount of transfer of financial instrument classified as an asset into (out of) level 3 of the fair value hierarchy.

+ References

No definition available.

+ Details

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- Definition

Amount of transfers of financial instrument classified as a liability into (out of) level 3 of the fair value hierarchy.

+ References

No definition available.

+ Details

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- Definition

The increase (decrease) during the period in the carrying value of derivative instruments reported as liabilities that are due to be disposed of within one year (or the normal operating cycle, if longer).

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 28
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=109223946&loc=d3e3602-108585

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Fair Value Measurements and Marketable Securities - Additional Information (Detail) - USD ($)	3 Months Ended		6 Months Ended	9 Months Ended		12 Months Ended
	Sep. 30, 2018	Sep. 30, 2017	Jun. 30, 2017	Sep. 30, 2018	Sep. 30, 2017	Dec. 31, 2017	Dec. 31, 2016	Mar. 31, 2016
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair value assets level 1 to level 2 transfers	$ 0	$ 0		$ 0	$ 0
Fair value assets level 2 to level 1 transfers	0	0		0	0
Fair value liabilities level 1 to level 2 transfers	0	0		0	0
Fair value liabilities level 2 to level 1 transfers	0	0		0	0
Transfer of financial asset into level 3 of fair value	0	0		0	0
Transfer of financial liabilities into level 3 of fair value	0	$ 0		0	$ 0
Spero Gyrase, Inc. [Member] \| Anti- dilution Rights [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Derivative liabilities	$ 200,000		$ 200,000	$ 200,000		$ 200,000		$ 1,600,000
Fair value inputs probability of funding						0.00%	100.00%
Decrease in derivative liability			$ 1,400,000