Government Contracts - Additional Information (Detail) $ in Thousands	1 Months Ended		12 Months Ended
	May 31, 2021 USD ($) Option	Jul. 31, 2018 USD ($)	Dec. 31, 2024 USD ($)	Dec. 31, 2023 USD ($)
Government Contracts [Line Items]
Grant revenue			$ 47,977	$ 103,781
Potential Amount of Committed Funding			59,300
Potential Amount of Uncommitted Funding			12,700
BARDA [Member]
Government Contracts [Line Items]
Potential contract amount awarded		$ 44,200	11,700
Potential amount increase in committed funding			59,300
Cumulative Revenue			56,700
BARDA [Member] | Base Period Contracts [Member]
Government Contracts [Line Items]
Potential amount initial funding awarded		$ 15,700
Contract term		3 years
BARDA [Member] | Grant [Member]
Government Contracts [Line Items]
Grant revenue			20,200	4,400
Niaid [Member]
Government Contracts [Line Items]
Cumulative Revenue			5,300
Potential Amount of Committed Funding			10,500
Committed amount from government contract			10,500
Niaid [Member] | SPR206 [Member]
Government Contracts [Line Items]
Contract term	5 years
Potential amount increase in committed funding	$ 3,400
Grant revenue			$ 400	$ 2,700
Award received for clinical development	$ 27,000
Niaid [Member] | First Option [Member] | SPR206 [Member]
Government Contracts [Line Items]
Number of option period for funding from government contract | Option	1