Equity - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands		12 Months Ended
	Sep. 21, 2022	Dec. 31, 2024	Dec. 31, 2023	Mar. 15, 2024	Mar. 11, 2021
Class Of Stock [Line Items]
Preferred stock, shares authorized		10,000,000	10,000,000
Common stock issued, aggregate fair value			$ 221
Common stock to be issued		$ 55	$ 53
GSK SPA [Member]
Class Of Stock [Line Items]
Issuance of stock, shares	7,450,000
Common stock issued, aggregate fair value	$ 10,300
GSK License Agreement [Member]
Class Of Stock [Line Items]
Issuance of stock, shares	7,450,000
Share price	$ 1.2
Common stock issued, aggregate fair value	$ 1,300
Common stock to be issued	$ 9,000
At-The-Market Offering Program [Member]
Class Of Stock [Line Items]
Issuance of stock, shares		0	144,476
Share price			$ 1.58
Gross proceeds from issuance of common and preferred stock			$ 200
At-The-Market Offering Program [Member] | Cantor Fitzgerald & Co [Member] | Maximum [Member]
Class Of Stock [Line Items]
Authorized offering value				$ 300,000	$ 300,000
Common stock available for issuance				$ 75,000	$ 75,000
Series A Convertible Preferred Stock [Member]
Class Of Stock [Line Items]
Issuance of stock, shares		2,220
Preferred stock, shares authorized		10,000,000
Series B Convertible Preferred Stock [Member]
Class Of Stock [Line Items]
Issuance of stock, shares		1,000
Preferred stock, shares authorized		10,000,000
Series C Convertible Preferred Stock [Member]
Class Of Stock [Line Items]
Issuance of stock, shares		3,333
Preferred stock, shares authorized		10,000,000
Series D Preferred Stock [Member]
Class Of Stock [Line Items]
Issuance of stock, shares		3,215,000
Preferred stock, shares authorized		10,000,000
Common Stock [Member]
Class Of Stock [Line Items]
Issuance of stock, shares			144,476