Accrued Expenses and Other Current Liabilities - Schedule of Accrued Expenses and Other Current Liabilities (Detail) - USD ($) $ in Thousands	Dec. 31, 2024	Dec. 31, 2023
Payables and Accruals [Abstract]
Accrued payroll and related expenses	$ 5,456	$ 3,339
Accrued external research and development expenses	9,493	2,274
Accrued professional fees	2,199	708
Accrued restructuring expenses	456	0
Accrued other	120	236
Total Accrued expenses and other current liabilities	$ 17,724	$ 6,557