Government Contracts - Additional Information (Detail) $ in Thousands		1 Months Ended		12 Months Ended
	Jul. 01, 2019 USD ($)	May 31, 2021 USD ($)	Jul. 31, 2018 USD ($)	Dec. 31, 2023 USD ($) Option	Dec. 31, 2022 USD ($)	Sep. 30, 2022 USD ($)	Jan. 19, 2022 USD ($)	Jan. 31, 2020 USD ($)	May 31, 2019 USD ($)
Government Contracts [Line Items]
Grant revenue				$ 103,781	$ 53,509
BARDA and DTRA [Member]
Government Contracts [Line Items]
Maximum potential funding from government contract				69,700
BARDA and Speros Achievement of Specified Milestones [Member]
Government Contracts [Line Items]
Potential grant amount exercised				12,700
Grant [Member] | DoD, CDMRP and JWMRP [Member]
Government Contracts [Line Items]
Grant revenue				0	1,000
SPR206 [Member] | DoD, CDMRP and JWMRP [Member]
Government Contracts [Line Items]
Award received for clinical development	$ 5,900
Non-dilutive funding period	4 years
BARDA [Member]
Government Contracts [Line Items]
Potential contract amount awarded			$ 44,200				$ 60,300
Potential amount additional funding awarded							12,900
Overall potential award increased							$ 47,600
Award received for clinical development						$ 12,900
BARDA [Member] | Base Period Contracts [Member]
Government Contracts [Line Items]
Potential amount initial funding awarded			$ 15,700
Potential amount additional funding awarded									$ 2,500
Overall potential award increased									46,800
Contract term			3 years
BARDA [Member] | Base Period Contracts [Member] | Maximum [Member]
Government Contracts [Line Items]
Potential amount initial funding awarded									18,200
BARDA [Member] | Base Period Contracts [Member] | Minimum [Member]
Government Contracts [Line Items]
Potential amount initial funding awarded									$ 15,700
BARDA [Member] | Grant [Member]
Government Contracts [Line Items]
Grant revenue				4,400	2,200
BARDA [Member] | First Option [Member]
Government Contracts [Line Items]
Potential amount additional funding awarded								$ 15,900
Potential Amount Subsequently Funding Awarded								600
Potential amount increase in committed funding								$ 34,700
BARDA [Member] | Second Option [member]
Government Contracts [Line Items]
Potential grant amount awarded				12,700
DTRA [Member] | Maximum [Member]
Government Contracts [Line Items]
Potential amount additional funding awarded				10,000
Niaid [Member] | SPR206 [Member]
Government Contracts [Line Items]
Contract term		5 years
Potential amount increase in committed funding				2,300
Grant revenue				2,700	$ 1,700
Award received for clinical development		$ 23,500
Niaid [Member] | First Option [Member] | SPR206 [Member]
Government Contracts [Line Items]
Potential amount increase in committed funding				$ 4,000
Number of option period for funding from government contract | Option				1
Niaid [Member] | Third Option [Member] | SPR206 [Member]
Government Contracts [Line Items]
Potential amount increase in committed funding				$ 800
Number of option period for funding from government contract | Option				3