Non-Controlling Interests - Spero Gyrase - Additional Information (Detail) - USD ($) $ in Thousands	12 Months Ended
Dec. 31, 2023	Dec. 31, 2022
Noncontrolling Interest [Line Items]
Common stock issued, aggregate fair value	$ 221	$ 14,234
Research and development expense	$ 51,440	$ 47,593

Equity impact of the value of new stock issued during the period. Includes shares issued in an initial public offering or a secondary public offering.

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