Equity - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands		1 Months Ended			9 Months Ended	12 Months Ended
	Sep. 21, 2022	Sep. 30, 2022	Jun. 30, 2022	Feb. 28, 2021	Sep. 30, 2022	Dec. 31, 2023	Dec. 31, 2022	Mar. 11, 2021
Class Of Stock [Line Items]
Preferred stock, shares authorized						10,000,000	10,000,000
Issuance of common stock, net of issuance costs						$ 221	$ 14,234
Common Stock, Shares Authorized						120,000,000	120,000,000
Common Stock, Value, Issued						$ 53	$ 52
GSK SPA [Member]
Class Of Stock [Line Items]
Issuance of stock, shares	7,450,000
Issuance of common stock, net of issuance costs	$ 10,300
GSK License Agreement [Member]
Class Of Stock [Line Items]
Issuance of stock, shares	7,450,000
Share price	$ 1.20805
Issuance of common stock, net of issuance costs	$ 1,300
Common Stock, Value, Issued	$ 9,000
At-The-Market Offering Program [Member]
Class Of Stock [Line Items]
Issuance of stock, shares						144,476	5,963,294
Share price						$ 1.58	$ 2.46
Gross proceeds from issuance of common and preferred stock						$ 200	$ 14,700
At-The-Market Offering Program [Member] | Cantor Fitzgerald & Co [Member] | Maximum [Member]
Class Of Stock [Line Items]
Authorized offering value								$ 300,000
Common stock available for issuance								$ 75,000
Series A Convertible Preferred Stock [Member]
Class Of Stock [Line Items]
Issuance of stock, shares						2,220
Preferred stock, shares authorized						10,000,000
Number of shares issuable upon conversion						1,000
Maximum percentage of common stock holding upon conversion of preferred stock						9.99%
Voting rights						no
Series B Convertible Preferred Stock [Member]
Class Of Stock [Line Items]
Issuance of stock, shares			938	62		1,000
Preferred stock, shares authorized						10,000,000
Number of shares issuable upon conversion			938,000	62,000		1,000
Maximum percentage of common stock holding upon conversion of preferred stock						9.99%
Voting rights						no
Series C Convertible Preferred Stock [Member]
Class Of Stock [Line Items]
Issuance of stock, shares		2,214				3,333
Preferred stock, shares authorized						10,000,000
Number of shares issuable upon conversion		2,214,000		73,000	2,214,000	1,000
Maximum percentage of common stock holding upon conversion of preferred stock						9.99%
Voting rights						no
Preferred stock, conversion basis				73
Series D Preferred Stock [Member]
Class Of Stock [Line Items]
Issuance of stock, shares						3,215,000
Preferred stock, shares authorized						10,000,000
Number of shares issuable upon conversion		2,273,000	942,000		2,273,000
Maximum percentage of common stock holding upon conversion of preferred stock						9.99%
Preferred stock, conversion basis			942,000		2,273,000	The shares of Series D Preferred Stock were convertible on a one-to-one basis into shares of common stock at any time at the option of the holder, provided that the holder was prohibited from converting the Series D Preferred Stock into shares of common stock if, as a result of such conversion, the holder, together with its affiliates, would own more than 9.99% of the total number of shares of common stock then issued and outstanding, subject to certain exceptions
Common Stock [Member]
Class Of Stock [Line Items]
Issuance of stock, shares						144,476	5,963,294
Issuance of common stock, net of issuance costs							$ 7