Share-Based Compensation - Summary of Share-Based Compensation Expense (Detail) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022	Sep. 30, 2023	Sep. 30, 2022
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based compensation	$ 1,908	$ 2,106	$ 5,935	$ 6,626
Research and development
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based compensation	619	730	2,006	2,595
General and Administrative Expenses [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based compensation	$ 1,289	$ 1,376	$ 3,929	$ 4,031