Restructuring - Additional Information (Details)			3 Months Ended
	May 31, 2023 USD ($)	Nov. 30, 2022 USD ($)	Mar. 31, 2023 USD ($)	Dec. 31, 2022 USD ($)	Dec. 31, 2021 Employee
Restructuring Cost and Reserve [Line Items]
Restructuring Charges			$ 0
Outstanding Accrued Expense			100,000
Common stock to be issued			53,000	$ 52,000
Performance-Based Awards [Member]
Restructuring Cost and Reserve [Line Items]
Compensation expense recognized			700,000
Performance-Based Awards [Member] | Minimum [Member]
Restructuring Cost and Reserve [Line Items]
Compensation expense recognized			$ 100
Human Capital Management Committee [Member]
Restructuring Cost and Reserve [Line Items]
Aggregate Retention Awards Cash Bonus		$ 1,100,000
Cash		200,000
Human Capital Management Committee [Member] | Subsequent Event [Member]
Restructuring Cost and Reserve [Line Items]
Aggregate Retention Awards Cash Bonus	$ 3,200,000
Cash	700,000
Tebipenem HBr Program [Member]
Restructuring Cost and Reserve [Line Items]
Number Of Employees Before Restructuring Initiative | Employee					146
Number Of Employees After Restructuring Initiative | Employee					41
Executive Retention Awards Member
Restructuring Cost and Reserve [Line Items]
Cash Bonus		$ 900,000
Executive Retention Awards Member | Subsequent Event [Member]
Restructuring Cost and Reserve [Line Items]
Common stock to be issued	$ 1,700,000