Share-Based Compensation (Tables)

3 Months Ended

Mar. 31, 2023

Share Based Compensation Arrangement By Share Based Payment Award [Line Items]

Summary of Stock Option Activity

The following table summarizes stock option activity under all equity plans (excluding RSUs) during the three months ended March 31, 2023:

	Number of Shares			Weighted Average Exercise Price		Weighted Average Contractual Term		Aggregate Intrinsic Value
						(in years)		(in thousands)
Outstanding as of December 31, 2022		3,979,099		$	10.99		5.27	$	1
Granted		46,413			1.74
Exercised		—			—
Forfeited or cancelled		(26,521	)		13.73
Outstanding as of March 31, 2023		3,998,991		$	10.87		4.94	$	1

Outstanding as of March 31, 2023 - vested and    expected to vest	3,998,991	$	10.87	4.94	$	1
Exercisable at March 31, 2023	2,971,459	$	9.95	4.38	$	—

Summary of Activity of Options and RSUs of Performance-Based Options

he following table summarizes RSU activity under all equity plans during the three months ended March 31, 2023:

	Number of RSU Shares			Weighted Average Grant Date Fair Value
Outstanding as of December 31, 2022		1,300,397		$	7.51
Granted		3,203,199			1.86
Vested and released		(115,618	)		11.18
Forfeited or cancelled		(13,875	)		14.83
Outstanding as of March 31, 2023		4,374,103		$	3.25

Summary of Share-Based Compensation Expense

The Company recorded share-based compensation expense related to incentive stock options, nonqualified stock options, stock grants, and stock-based awards in the following expense categories of its consolidated statements of operations and comprehensive loss (in thousands):

Three Months Ended March 31,
2023	2022

Research and development expenses	$	798	$	1,363
General and administrative expenses		1,372		1,840
Total	$	2,170	$	3,203